Liu William J, Sesay Foday R, Coursier Antoine, Knust Barbara, Marrinan Jaclyn E, Whitmer Shannon, McDonald Suzanna L R, Gaillard Philippe, Liu Yang, Su Qiudong, Zhang Yong, Crozier Ian, Ariyarajah Archchun, Carino Marylin, Massaquoi Thomas, Broutet Nathalie, Xu Wenbo, Wu Guizhen, Ströher Ute, Gao George F, Formenty Pierre, Sahr Foday, Deen Gibrilla F
NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
The Sierra Leone Ministry of Defense, Freetown, Sierra Leone.
Open Forum Infect Dis. 2019 Feb 26;6(3):ofz068. doi: 10.1093/ofid/ofz068. eCollection 2019 Mar.
The clinical, virologic, and immunologic findings in a female Ebola virus disease patient are described. During the long-term follow-up, Ebola virus RNA was detectable in vaginal fluid before 36 days after symptom onset, with nearly an identical genome sequence as in acute phase blood. Ebola-specific T cells retained activation at 56 days after disease onset.
描述了一名女性埃博拉病毒病患者的临床、病毒学和免疫学发现。在长期随访期间，症状出现后36天内，阴道液中可检测到埃博拉病毒RNA，其基因组序列与急性期血液中的几乎相同。埃博拉特异性T细胞在疾病发作后56天仍保持激活状态。
