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疼痛灾难化对 PTSD 症状和疼痛结局的中介作用。

The Mediating Effect of Pain Catastrophizing on PTSD Symptoms and Pain Outcome.

机构信息

Mayo Clinic, Rochester, MN.

Mary Free Bed Rehabilitation Hospital.

出版信息

Clin J Pain. 2019 Jul;35(7):583-588. doi: 10.1097/AJP.0000000000000713.

DOI:10.1097/AJP.0000000000000713
PMID:30950871
Abstract

OBJECTIVE

Coprevalence of chronic pain and posttraumatic stress disorder (PTSD) negatively impacts the course of both disorders. Patients diagnosed with both conditions report greater pain, affective distress, and disability when compared with those with either chronic pain or PTSD alone. While the prevalence and complexity of the comorbidity is widely acknowledged, there is a dearth of research examining potential mechanism variables that might account for the relationship between chronic pain and PTSD. The current study utilizes a series of mediation analyses to examine if pain catastrophizing mediates the relationship between PTSD symptomatology and chronic pain outcome.

MATERIALS AND METHODS

A total of 203 treatment-seeking participants admitted to a 3-week interdisciplinary pain rehabilitation program completed a battery of psychometrically validated measures of pain severity, pain interference, pain catastrophizing, depressive symptoms, and PTSD symptoms at program admission.

RESULTS

A series of multiple parallel mediation analyses revealed that pain catastrophizing fully mediated the relationships between PTSD symptoms and pain outcome (ie, pain severity and pain interference) above and beyond the influence of depressive symptoms.

DISCUSSION

Results suggest that pain catastrophizing may represent an important cognitive mechanism through which PTSD symptoms influence the experience of chronic pain. Psychosocial treatment approaches that directly target tendency to catastrophize in response to pain may hold the potential to have salutary effects on both chronic pain and PTSD.

摘要

目的

慢性疼痛和创伤后应激障碍(PTSD)的共病患病率对这两种疾病的病程都有负面影响。与仅患有慢性疼痛或 PTSD 的患者相比,同时患有这两种疾病的患者报告的疼痛、情感困扰和残疾程度更大。尽管共病的患病率和复杂性得到了广泛认可,但研究潜在的机制变量以解释慢性疼痛和 PTSD 之间关系的研究却很少。本研究采用一系列中介分析来检验疼痛灾难化是否在 PTSD 症状与慢性疼痛结果之间起中介作用。

材料和方法

共有 203 名寻求治疗的参与者参加了为期 3 周的跨学科疼痛康复计划,在计划开始时完成了一系列心理测量验证的疼痛严重程度、疼痛干扰、疼痛灾难化、抑郁症状和 PTSD 症状的测量。

结果

一系列平行中介分析表明,疼痛灾难化完全中介了 PTSD 症状与疼痛结果(即疼痛严重程度和疼痛干扰)之间的关系,超过了抑郁症状的影响。

讨论

结果表明,疼痛灾难化可能是 PTSD 症状影响慢性疼痛体验的一个重要认知机制。直接针对对疼痛的灾难化倾向的心理社会治疗方法可能对慢性疼痛和 PTSD 都有有益的影响。

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