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全球肺功能倡议参考方程是否反映了中东成年人群样本?

Do the global lung function initiative reference equations reflect a sample of adult Middle Eastern population?

作者信息

Al-Qerem Walid A, Hammad Alaa M, AlQirem Rania A, Ling Jonathan

机构信息

Department of Pharmacy, College of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan.

Faculty of Health Sciences and Wellbeing, University of Sunderland, Sunderland, UK.

出版信息

Clin Respir J. 2019 Jul;13(7):429-437. doi: 10.1111/crj.13027. Epub 2019 Apr 22.

DOI:10.1111/crj.13027
PMID:30951244
Abstract

INTRODUCTION

The global lung function initiative (GLI) 2012 introduced new multi-ethnic spirometry reference values for numerous ethnicities.

OBJECTIVES

The aim of this study was to investigate the suitability of the GLI reference values for the adult Jordanian population.

METHODS

About 1875 (1029 females and 846 males) healthy non-smoking adults were enrolled from several locations in Jordan. Spirometry tests were performed. z-scores and predicted normal values were calculated for each participant using GLI 2012 equations in addition to other local equations from the Middle East.

RESULTS

Our results indicated that none of the GLI 2012 or other regional equations studied produced an acceptable fit to our data.

CONCLUSION

A need to formulate a specific equation for the Jordanian population is urgently required to better evaluate their respiratory conditions.

摘要

引言

全球肺功能倡议(GLI)2012年为众多种族推出了新的多民族肺量计参考值。

目的

本研究旨在调查GLI参考值对约旦成年人群的适用性。

方法

从约旦的多个地点招募了约1875名(1029名女性和846名男性)健康非吸烟成年人。进行了肺量计测试。除了中东地区的其他本地方程外,还使用GLI 2012方程为每个参与者计算了z分数和预测正常值。

结果

我们的结果表明,所研究的GLI 2012方程或其他区域方程均未与我们的数据产生可接受的拟合。

结论

迫切需要为约旦人群制定特定方程,以更好地评估他们的呼吸状况。

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