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[硝酸甘油在心肌梗死中的药效学]

[Nitroglycerin pharmacodynamics in myocardial infarct].

作者信息

Orlov L L, Shilov A M, Sviridov A A, Sheĭnberg B V, Borisov V G

出版信息

Farmakol Toksikol. 1986 Sep-Oct;49(5):80-4.

PMID:3095139
Abstract

The experience of treating 2,500 patients with acute myocardial infarction enabled the authors to prove a diverse character of nitroglycerin effect: it exerts a positive inotropic action on the myocardium, improves elastic properties of the myocardium, normalizes energy balance of the myocardium, influences the system of the blood aggregate state through contractile elements of platelets producing a hypocoagulatory effect.

摘要

对2500例急性心肌梗死患者的治疗经验使作者得以证实硝酸甘油作用具有多样性:它对心肌发挥正性肌力作用,改善心肌弹性特性,使心肌能量平衡正常化,通过血小板收缩成分影响血液聚集状态系统,产生低凝效应。

相似文献

1
[Nitroglycerin pharmacodynamics in myocardial infarct].[硝酸甘油在心肌梗死中的药效学]
Farmakol Toksikol. 1986 Sep-Oct;49(5):80-4.
2
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[The use of verapamil for correcting the hemodynamic disorders in the acute period of a myocardial infarct].[维拉帕米在心肌梗死急性期纠正血流动力学紊乱中的应用]
Vrach Delo. 1990 Sep(9):6-8.
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[Effect of obzidan and nitroglycerin on heart chamber function in acute myocardial infarct (based on echocardiographic data)].
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[Hemodynamics effect of sublingual nitroglycerin in the acute phase of myocardial infarct].[舌下硝酸甘油对心肌梗死急性期的血流动力学影响]
Rev Esp Cardiol. 1979;32(2):183-92.
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[Immediate effect of furosemide on the hemodynamics of post-infarct patients during rest and under ergometric stress. A comparison with the effect of nitroglycerin].
Verh Dtsch Ges Inn Med. 1975;81:303-6.
7
[Effect of nitroglycerin treatment on left ventricular contractile function in the acute period of myocardial infarct].
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR. 1981;4(1):46-50.
8
Effect of nitroglycerin on systemic hemodynamics and local contractile state in experimental myocardial infarction: comparison with the effects of pressure, volume and heart rate changes.硝酸甘油对实验性心肌梗死时全身血流动力学及局部收缩状态的影响:与压力、容量及心率变化的影响比较
Kobe J Med Sci. 1975 Dec;21(4):117-34.
9
[Nitroglycerin in patients following acute myocardial infarct].
Acta Univ Palacki Olomuc Fac Med. 1984;107:247-51.
10
[Effect of nitroglycerin during acute period of myocardial infarction].
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