Cook Jesse D, Eftekari Sahand C, Leavitt Lydia A, Prairie Michael L, Plante David T
Department of Psychiatry, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin.
Department of Psychology, University of Wisconsin-Madison, Madison, Wisconsin.
J Clin Sleep Med. 2019 Apr 15;15(4):597-602. doi: 10.5664/jcsm.7722.
To determine the optimal Actiwatch 2 setting configuration for the estimation of total sleep time (TST) in persons with suspected idiopathic hypersomnia.
Thirty-three patients with a diagnosis of idiopathic hypersomnia (28 female; mean age = 33.7 ± 10.5) underwent ad libitum polysomnography with concurrent use of the Actiwatch 2. Actiwatch 2 sleep-wake activity threshold (SWAT; Low, Medium, and High) and sleep immobility onset and offset (SIOO; 5, 10, 15, 20, 25, and 30 epoch) duration were modified during data processing. The resultant 18 unique setting combinations were subsequently evaluated using Bland-Altman and epoch comparison analyses to determine optimal settings relative to polysomnography.
Low SWAT + 25 Epoch SIOO displayed the least divergence from polysomnography (mean difference 3.4 minutes). Higher SWAT and lower SIOO increased sensitivity and accuracy, but at the expense of reducing specificity and the ability to accurately estimate TST.
These results demonstrate that actigraphic settings should be carefully considered when estimating sleep duration. The Low + 25 Epoch configuration is indicated as most optimal for estimating TST in persons with suspected idiopathic hypersomnia.
A commentary on this article appears in this issue on page 539.
确定用于估计疑似特发性发作性睡病患者总睡眠时间（TST）的最佳Actiwatch 2设置配置。
33例诊断为特发性发作性睡病的患者（28例女性；平均年龄 = 33.7 ± 10.5）在自由睡眠状态下接受多导睡眠图检查，同时使用Actiwatch 2。在数据处理过程中，对Actiwatch 2的睡眠-清醒活动阈值（SWAT；低、中、高）以及睡眠静止开始和结束（SIOO；5、10、15、20、25和30个时段）持续时间进行了修改。随后，使用Bland-Altman分析和时段比较分析对得到的18种独特设置组合进行评估，以确定相对于多导睡眠图的最佳设置。
低SWAT + 25时段SIOO与多导睡眠图的差异最小（平均差异3.4分钟）。较高的SWAT和较低的SIOO提高了敏感性和准确性，但以降低特异性和准确估计TST的能力为代价。
这些结果表明，在估计睡眠时间时应仔细考虑活动记录仪的设置。低 + 25时段配置被认为是估计疑似特发性发作性睡病患者TST的最佳设置。
关于本文的一篇评论发表在本期第539页。
