用嵌合抗原受体T细胞疗法紧急刹车狼疮病情
Slamming the brakes on lupus with CAR T cells.
作者信息
Clark Rachael A
机构信息
Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA. Email:
出版信息
Sci Immunol. 2019 Apr 5;4(34). doi: 10.1126/sciimmunol.aax3916.
PMID:30952806
Abstract
Sustained depletion of B cells with CAR T cells induces disease remission in lupus-prone mice.
摘要
用嵌合抗原受体（CAR）T细胞持续清除B细胞可诱导狼疮易感小鼠的疾病缓解。
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