Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow, UP, India.
Trans R Soc Trop Med Hyg. 2019 Jul 1;113(7):418-423. doi: 10.1093/trstmh/trz018.
Patients with neurocysticercosis (NCC) may have an increased frequency of migraine. We studied the characteristics of migraine attacks in patients with calcified NCC on brain imaging.
Of 350 migraine patients who visited our outpatient department from January 2016 through June 2018, 166 had undergone brain imaging. Seventy-two patients with migraines had calcified NCC. The migraine attacks of the patients with calcification (MiC) were compared with those of 94 patients without calcification (MiNC).
Side-locked headaches were seen in 48.6% of the MiC patients. Aura preceding the migraine attack was more common in the MiC group than in the MiNC group (22.22% vs 7.4%; p=0.001). The MiC group had fewer headache episodes per month (5 vs 6; p<0.0001) with fewer common associated features (62.5% vs 84.1%; p=0.006). They also required fewer drugs for secondary prophylaxis (2 vs 3; p=0.002).
Some of the clinical characteristics of migraine attacks are sufficiently different in patients with and without NCC. This may suggest some influence of NCC in the pathophysiology of migraine to account for alterations in the clinical manifestations of the disease. Whether this difference could be inferred as NCC having a causative role in migraine needs further research.
神经囊尾蚴病（NCC）患者偏头痛发作的频率可能会增加。我们研究了脑影像学显示有钙化性 NCC 的患者偏头痛发作的特点。
2016 年 1 月至 2018 年 6 月期间，我们的门诊共接待了 350 名偏头痛患者，其中 166 名患者进行了脑部成像。72 名偏头痛患者患有钙化性 NCC。将钙化患者（MiC）的偏头痛发作与 94 名无钙化患者（MiNC）的偏头痛发作进行了比较。
48.6%的 MiC 患者出现单侧头痛。MiC 组比 MiNC 组更常见偏头痛发作前先兆（22.22% vs 7.4%；p=0.001）。MiC 组每月偏头痛发作次数较少（5 次 vs 6 次；p<0.0001），常见伴随症状较少（62.5% vs 84.1%；p=0.006）。他们也需要更少的药物进行二级预防（2 种 vs 3 种；p=0.002）。
NCC 患者和无 NCC 患者的偏头痛发作的一些临床特征存在明显差异。这可能表明 NCC 对偏头痛的病理生理学有一定影响，从而改变了疾病的临床表现。这种差异是否可以推断为 NCC 是偏头痛的病因，还需要进一步研究。
