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客观测试在儿童哮喘诊断中的作用。

The role of objective tests to support a diagnosis of asthma in children.

机构信息

Leicester Children's Hospital, University Hospitals of Leicester, Leicester Royal Infirmary, Leicester LE1 5WW, UK; Paediatric Clinical Investigation Centre, Leicester National Institute for Health Research Biomedical Research Centre (Respiratory theme), University of Leicester, Leicester Royal Infirmary, Leicester LE2 7LX, UK.

Paediatric Clinical Investigation Centre, Leicester National Institute for Health Research Biomedical Research Centre (Respiratory theme), University of Leicester, Leicester Royal Infirmary, Leicester LE2 7LX, UK.

出版信息

Paediatr Respir Rev. 2020 Feb;33:52-57. doi: 10.1016/j.prrv.2019.02.001. Epub 2019 Feb 28.

Abstract

In many healthcare settings asthma in children is a clinical diagnosis based on parental reported symptoms. These include intermittent episodes of wheezing, breathlessness and periodic nocturnal dry cough. Increased symptoms often coincide with colds. Confirming a diagnosis of asthma in children can be difficult and recent reports highlight that misdiagnosis, including over- and under-diagnosis of asthma are common. Recent UK National Institute of Health and Care Excellence guidelines recommend diagnostic algorithms for children from five years and adults to support a clinical suspicion of asthma. Spirometry, bronchodilator reversibility and fractional exhaled nitric oxide testing are the first line tests to diagnose asthma in children. The introduction of these tests across all healthcare settings has the potential to reduce misdiagnosis, improve asthma management and reduce healthcare spending for asthma.

摘要

在许多医疗保健环境中,儿童哮喘是一种基于家长报告症状的临床诊断。这些症状包括间歇性喘息、呼吸困难和周期性夜间干咳。症状加重通常与感冒同时发生。确认儿童哮喘的诊断可能具有挑战性,最近的报告强调,误诊,包括过度诊断和漏诊哮喘很常见。最近英国国家卫生与保健卓越研究所指南建议从五岁儿童和成年人开始使用诊断算法,以支持对哮喘的临床怀疑。肺量测定、支气管扩张剂可逆性和呼出气一氧化氮分数检测是诊断儿童哮喘的一线检查。在所有医疗保健环境中引入这些检查有可能减少误诊,改善哮喘管理,并降低哮喘的医疗保健支出。

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