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美国墨西哥裔 2 型糖尿病西班牙裔/拉丁美洲人群中口服降糖药低依从性的相关因素。

Correlates of low-adherence to oral hypoglycemic medications among Hispanic/Latinos of Mexican heritage with Type 2 Diabetes in the United States.

机构信息

Division of Health Promotion and Behavioral Science, School of Public Health, San Diego State University and Institute for Behavioral and Community Health, 9245 Sky Park Court, Suite 221 San Diego, CA 92123-4311, USA; Department of Family Medicine and Public Health, School of Medicine and Women's Cardiovascular Research Center, University of California San Diego, 8950 Villa La Jolla Drive, Suite A2016, La Jolla, CA 92307, USA.

Division of Health Promotion and Behavioral Science, School of Public Health, San Diego State University and Institute for Behavioral and Community Health, 9245 Sky Park Court, Suite 221 San Diego, CA 92123-4311, USA.

出版信息

Diabetes Res Clin Pract. 2019 Sep;155:107692. doi: 10.1016/j.diabres.2019.04.007. Epub 2019 Apr 4.

Abstract

AIMS

We examined psychosocial- and social/economic factors related to low medication adherence, and sex differences, among 279 adults of Mexican heritage with Type 2 Diabetes.

METHODS

Self-report and health record data were used for cross-sectional analyses. Bivariate analyses tested the association of demographic, psychosocial (depression, anxiety, stress) and social/economic factors (insurance type, health literacy, social support) and medication adherence measured by proportion of days covered. Hierarchical regression analyses examined associations between demographic, psychosocial- and social/economic- related factors and low medication adherence stratified by sex.

RESULTS

More males than females demonstrated low adherence to hypoglycemic medications (75.0.% vs. 70.3%) (p < 0.05). We found significant differences between levels social support and medication adherence (p < 0.05). In hierarchical models, being US born and higher levels of social support were associated with low adherence among males (p < 0.05, and p < 0.001).

CONCLUSIONS

Approximately 72% of Mexican heritage adults demonstrated low adherence (PDC ≤ 0.50) to their hypoglycemic regimen, and gender differences exist. Interventions should address gender differences in preferences for social support to improve medication-taking behaviors among Mexican heritage males.

摘要

目的

我们研究了与 279 名墨西哥裔 2 型糖尿病成人的低药物依从性相关的社会心理和社会/经济因素,以及性别差异。

方法

使用自我报告和健康记录数据进行横断面分析。双变量分析测试了人口统计学、社会心理(抑郁、焦虑、压力)和社会/经济因素(保险类型、健康素养、社会支持)与通过覆盖天数衡量的药物依从性之间的关联。分层回归分析根据性别检查了与人口统计学、社会心理和社会/经济相关因素与低药物依从性之间的关联。

结果

与女性相比,更多的男性表现出对降血糖药物的低依从性(75.0%对 70.3%)(p<0.05)。我们发现社会支持水平与药物依从性之间存在显著差异(p<0.05)。在分层模型中,出生于美国和较高水平的社会支持与男性的低依从性相关(p<0.05 和 p<0.001)。

结论

大约 72%的墨西哥裔成年人对其降血糖方案的依从性较低(PDC≤0.50),且存在性别差异。干预措施应针对社会支持偏好的性别差异,以改善墨西哥裔男性的服药行为。

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