Lisbon Psychiatric Hospital, Lisbon, Portugal.
Medical Unit, Pfizer, Porto Salvo, Portugal.
Health Qual Life Outcomes. 2015 Apr 25;13:50. doi: 10.1186/s12955-015-0244-2.
Generalized anxiety disorder has a strong impact on health-related quality of life. For this reason, it seems relevant to develop strategies allowing early diagnoses in order to promote appropriate treatments. The objective of this study was to culturally adapt and validate the GAD-7 for the Portuguese patients with generalized anxiety disorder.
For the cultural adaptation of the Portuguese version of the GAD-7 scale we started with a previous translation made by Mapi Institute and decided to perform a clinical review followed by a cognitive debriefing with patients. Once piloted, this version was then tested in a larger sample for feasibility and reliability (1-week test-retest). Construct validity was assessed by the relationship between GAD-7 and socio-demographic and clinical variables. Its unidimensionality was tested by principal component factor analysis. Criterion validity was assessed by comparing GAD-7 scores with those obtained by HADS, and EQ-5D. STAI was mainly used as a screening indicator for patient inclusion.
GAD-7 was considered feasible with a mean completion time of 2.3 minutes and no major floor or ceiling effects. We found an excellent Cronbach's alpha internal consistency score (0.880) and the test-retest and interclass correlation coefficients were also very good. Regarding the construct validity, younger patients, those with higher education, employed and without anxiety symptoms revealed lower GAD-7 scores, meaning better health. The unidimensionality of GAD-7 index was also confirmed by principal component factor analysis. At last, GAD-7 was significantly correlated with other health outcome indices and the classification levels created by it and by HADS showed to be dependent.
The excellent metric properties confirmed the cultural adaptation and validity of GAD-7 into Portuguese population, allowing the clinicians an early detection and treatment of these patients.
广泛性焦虑障碍对健康相关生活质量有很大的影响。因此,开发早期诊断策略以促进适当的治疗似乎很重要。本研究的目的是为葡萄牙的广泛性焦虑障碍患者对 GAD-7 进行文化调适和验证。
我们从 Mapi 研究所之前翻译的葡萄牙语版本开始对 GAD-7 量表进行文化调适,并决定进行临床审查,然后对患者进行认知剖析。在试点后,我们在更大的样本中对该版本进行了可行性和可靠性测试(1 周的测试-重测)。通过 GAD-7 与社会人口统计学和临床变量之间的关系评估结构效度。通过主成分因子分析测试其维度。通过与 HADS 和 EQ-5D 比较 GAD-7 评分来评估效标效度。STAI 主要用作患者纳入的筛选指标。
GAD-7 被认为是可行的,平均完成时间为 2.3 分钟,没有明显的地板或天花板效应。我们发现内部一致性 Cronbach's alpha 评分非常好(0.880),测试-重测和组内相关系数也非常好。关于结构效度,年轻患者、受教育程度较高、有工作和没有焦虑症状的患者 GAD-7 评分较低,意味着健康状况较好。主成分因子分析也证实了 GAD-7 指数的维度。最后,GAD-7 与其他健康结果指标显著相关,并且由它和 HADS 创建的分类水平是相互依赖的。
优秀的计量学特性证实了 GAD-7 在葡萄牙人群中的文化调适和有效性,使临床医生能够早期发现和治疗这些患者。