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粪便钙卫蛋白作为炎症性肠病的筛查标志物。

Fecal Calprotectin as a Screening Marker for Inflammatory Bowel Disease.

机构信息

Department of Pediatrics, Apollo Children's Hospital, Chennai, India.

出版信息

Indian Pediatr. 2019 Mar 15;56(3):249-250.

PMID:30955002
Abstract

We compared fecal calprotectin and endoscopic findings of 53 children with possible inflammatory bowel disease and found an optimal cut-off of 68 µg/g in Receiver operative curve [AUC 0.88 (95% CI 0.79, 0.97)] to discriminate inflammatory bowel disease with other inflammatory gastrointestinal conditions.

摘要

我们比较了 53 例疑似炎症性肠病患儿的粪便钙卫蛋白和内镜检查结果,发现接收者工作特征曲线 [AUC 0.88(95%CI 0.79, 0.97)] 区分炎症性肠病与其他炎症性胃肠道疾病的最佳截断值为 68 µg/g。

相似文献

1
Fecal Calprotectin as a Screening Marker for Inflammatory Bowel Disease.粪便钙卫蛋白作为炎症性肠病的筛查标志物。
Indian Pediatr. 2019 Mar 15;56(3):249-250.
2
Fecal calprotectin levels in children is more tightly associated with histological than with macroscopic endoscopy findings.儿童粪便钙卫蛋白水平与组织学检查结果的相关性比与宏观内镜检查结果的相关性更为紧密。
Clin Lab. 2014;60(12):1993-2000. doi: 10.7754/clin.lab.2014.140203.
3
Colorectal inflammation is well predicted by fecal calprotectin in children with gastrointestinal symptoms.粪便钙卫蛋白能很好地预测有胃肠道症状儿童的结肠直肠炎症。
J Pediatr Gastroenterol Nutr. 2005 Apr;40(4):450-5. doi: 10.1097/01.mpg.0000154657.08994.94.
4
Predicting inflammatory bowel disease in children with abdominal pain and diarrhoea: calgranulin-C versus calprotectin stool tests.预测腹痛和腹泻儿童的炎症性肠病:钙粒蛋白-C 与钙卫蛋白粪便检测。
Arch Dis Child. 2018 Jun;103(6):565-571. doi: 10.1136/archdischild-2017-314081. Epub 2018 Mar 7.
5
Faecal calprotectin, an useful marker in discriminating between inflammatory bowel disease and functional gastrointestinal disorders.粪便钙卫蛋白是区分炎症性肠病和功能性胃肠疾病的有用标志物。
Gastroenterol Hepatol. 2017 Mar;40(3):125-131. doi: 10.1016/j.gastrohep.2016.04.009. Epub 2016 May 31.
6
Fecal hemoglobin and calprotectin are equally effective in identifying patients with inflammatory bowel disease with active endoscopic inflammation.粪便血红蛋白和钙卫蛋白在识别患有内镜下活动性炎症的炎症性肠病患者方面同样有效。
Inflamm Bowel Dis. 2014 Feb;20(2):307-14. doi: 10.1097/01.MIB.0000438428.30800.a6.
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Fecal calprotectin as a promising marker of inflammatory diseases.粪便钙卫蛋白作为一种有前景的炎症性疾病标志物。
Bratisl Lek Listy. 2009;110(10):598-602.
8
[Assessment of fecal calprotectin concentration as inflammatory marker in inflammatory bowel diseases in children--preliminary report].[儿童炎症性肠病中粪便钙卫蛋白浓度作为炎症标志物的评估——初步报告]
Pol Merkur Lekarski. 2010 Oct;29(172):241-6.
9
Low fecal calprotectin predicts sustained clinical remission in inflammatory bowel disease patients: a plea for deep remission.粪便钙卫蛋白水平低可预测炎症性肠病患者的持续临床缓解:呼吁深度缓解。
J Crohns Colitis. 2015 Jan;9(1):50-5. doi: 10.1093/ecco-jcc/jju003. Epub 2014 Nov 26.
10
Avoid Endoscopy in Children With Suspected Inflammatory Bowel Disease Who Have Normal Calprotectin Levels.对于疑似炎症性肠病但钙卫蛋白水平正常的儿童,避免进行内镜检查。
J Pediatr Gastroenterol Nutr. 2016 Jan;62(1):47-9. doi: 10.1097/MPG.0000000000000939.

引用本文的文献

1
The use of calgranulin-C (S100A12) and fecal zonulin as possible non-invasive markers in children with inflammatory bowel disease: a clinical study.钙粒蛋白-C(S100A12)和粪便连蛋白作为炎症性肠病患儿可能的非侵入性标志物的应用:一项临床研究。
Eur J Pediatr. 2023 Mar;182(3):1299-1308. doi: 10.1007/s00431-022-04771-7. Epub 2023 Jan 13.