Department of Psychology, William Paterson University, Wayne, New Jersey, USA.
Arch Suicide Res. 2020;24(sup2):S381-S390. doi: 10.1080/13811118.2019.1592041. Epub 2019 May 10.
The purpose of this study was to test the association between arousal in response to psychological stress, as measured by standardized maximum decrease in high-frequency heart rate variability (HF HRV) during a stressful laboratory task, and current suicide ideation (SI). 81 emerging adult college students completed a stressful laboratory task consisting of the computerized Stroop and Cyberball while having their heart activity recorded. Spectral analysis and Fast Fourier transformations were used to decompose and transform the recording into the high (0.15 Hz-0.4 Hz) frequency component. After the task, participants completed the Beck Scale for Suicide Ideation to measure current SI, the Beck Depression Inventory-II to assess depressive symptom severity, and a brief medical history. Multivariate negative binomial regression analysis showed that the negative association between SI and arousal in response to psychological stress remained statistically significant when suicide attempt history, depressive symptom severity, female gender, and current smoking behavior were controlled. Identification of potential biomarkers for SI is important for suicide behavior prevention given limits to self-report SI assessment. Our results suggest arousal in response to psychological stress merits further consideration as a biomarker for current SI.
这项研究的目的是检验心理应激反应中的唤醒程度与当前自杀意念（SI）之间的关联，唤醒程度通过在应激实验室任务中高频心率变异性（HF HRV）的最大下降幅度来衡量。81 名成年初期大学生完成了一项包括计算机化 Stroop 和 Cyberball 的应激实验室任务，同时记录他们的心率活动。频谱分析和快速傅里叶变换用于将记录分解并转换为高频（0.15 Hz-0.4 Hz）频率分量。任务结束后，参与者完成了贝克自杀意念量表以测量当前的 SI，贝克抑郁量表-第二版以评估抑郁症状严重程度，并填写简要的医疗史。多变量负二项式回归分析显示，在控制自杀尝试史、抑郁症状严重程度、女性性别和当前吸烟行为后，SI 和心理应激反应之间的负相关仍然具有统计学意义。鉴于自我报告的 SI 评估存在局限性，识别潜在的 SI 生物标志物对于预防自杀行为非常重要。我们的研究结果表明，心理应激反应中的唤醒程度值得进一步考虑作为当前 SI 的生物标志物。
