Yonekura M, Kaminogou M, Fujiita Y, Mori K, Yokoyama S
No Shinkei Geka. 1978 Sep;6(9):931-4.
A rare case of the choroid plexus papilloma originating from the extraventricle was reported. A 48-hear-old woman began not to walk well about two years ago. Then, she was complained of vertigo, hearing disturbance of the right ear and nausea. These symptoms gradually increased. On admission she had papilledema, Brun's nystagmus, hearing disturbance of right ear and cerebellar ataxia. Cerebral angiogram and CT scan showed dilated ventricles and a large tumor in the posterior fossa. At operation, tumor was found in extramedullary space at the right cerebello-pontine angle and extended to the foramen magnum. This was removed totally. Histological examination revealed choroid plexus papilloma. Her postoperative course was satisfactory and shunting procedure was not necessary. According to the electron microscopic findings, the ultrastructure of tumor was similar to that of normal choroid plexus. We could not clear the morphological features which were considered essential for overproduction of CSF in the tumor.
报告了一例罕见的起源于脑室外的脉络丛乳头状瘤病例。一名48岁女性大约两年前开始行走不稳。随后,她出现眩晕、右耳听力障碍和恶心。这些症状逐渐加重。入院时,她有视乳头水肿、布伦斯眼球震颤、右耳听力障碍和小脑共济失调。脑血管造影和CT扫描显示脑室扩张,后颅窝有一个大肿瘤。手术时,在右侧小脑桥脑角的髓外间隙发现肿瘤,并延伸至枕骨大孔。肿瘤被完全切除。组织学检查显示为脉络丛乳头状瘤。她的术后过程令人满意,无需进行分流手术。根据电子显微镜检查结果,肿瘤的超微结构与正常脉络丛相似。我们无法明确肿瘤中脑脊液过度产生所必需的形态学特征。