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Proc (Bayl Univ Med Cent). 2018 Nov 13;32(1):110-112. doi: 10.1080/08998280.2018.1503479. eCollection 2019 Jan.
2
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本文引用的文献

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Antiplatelet and anticoagulant agents for secondary prevention of stroke and other thromboembolic events in people with antiphospholipid syndrome.抗血小板和抗凝药物用于抗磷脂综合征患者中风和其他血栓栓塞事件的二级预防。
Cochrane Database Syst Rev. 2017 Oct 2;10(10):CD012169. doi: 10.1002/14651858.CD012169.pub2.
2
Rivaroxaban versus warfarin to treat patients with thrombotic antiphospholipid syndrome, with or without systemic lupus erythematosus (RAPS): a randomised, controlled, open-label, phase 2/3, non-inferiority trial.利伐沙班与华法林治疗血栓形成性抗磷脂综合征患者（无论是否合并系统性红斑狼疮）（RAPS）：一项随机、对照、开放标签的2/3期非劣效性试验。
Lancet Haematol. 2016 Sep;3(9):e426-36. doi: 10.1016/S2352-3026(16)30079-5.
3
Recurrent stent thrombosis in a patient with antiphospholipid syndrome and dual anti-platelet therapy non-responsiveness.抗磷脂综合征患者双联抗血小板治疗无效致支架内血栓再发
Korean Circ J. 2015 Jan;45(1):71-6. doi: 10.4070/kcj.2015.45.1.71. Epub 2015 Jan 26.
4
Antiphospholipid syndrome and the heart: a case series and literature review.抗磷脂综合征与心脏：病例系列及文献复习。
Autoimmun Rev. 2015 Mar;14(3):214-22. doi: 10.1016/j.autrev.2014.11.003. Epub 2014 Nov 12.
5
Antiphospholipid syndrome and acute myocardial infarction: treatment with thrombectomy and abciximab.抗磷脂综合征与急性心肌梗死：采用血栓切除术和阿昔单抗治疗
Rev Port Cardiol. 2014 Jul-Aug;33(7-8):465.e1-4. doi: 10.1016/j.repc.2014.01.020. Epub 2014 Aug 13.
6
Long-term outcome of patients with antiphospholipid syndrome who undergo percutaneous coronary intervention.接受经皮冠状动脉介入治疗的抗磷脂综合征患者的长期预后。
Cardiology. 2012;122(2):76-82. doi: 10.1159/000338347. Epub 2012 Jun 20.
7
Task Force on Catastrophic Antiphospholipid Syndrome (APS) and Non-criteria APS Manifestations (I): catastrophic APS, APS nephropathy and heart valve lesions.工作组关于灾难性抗磷脂综合征（APS）和非标准 APS 表现（一）：灾难性 APS、APS 肾病和心脏瓣膜病变。
Lupus. 2011 Feb;20(2):165-73. doi: 10.1177/0961203310395051.
8
Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).静脉血栓栓塞性疾病的抗栓治疗：美国胸科医师学会循证临床实践指南（第8版）
Chest. 2008 Jun;133(6 Suppl):454S-545S. doi: 10.1378/chest.08-0658.
9
International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS).关于明确抗磷脂综合征（APS）分类标准更新的国际共识声明。
J Thromb Haemost. 2006 Feb;4(2):295-306. doi: 10.1111/j.1538-7836.2006.01753.x.
10
Five-year follow-up by transesophageal echocardiographic studies in primary antiphospholipid syndrome.原发性抗磷脂综合征经食管超声心动图检查的五年随访
Am J Cardiol. 2005 Aug 15;96(4):574-9. doi: 10.1016/j.amjcard.2005.04.022.

一名患有巨大左心室血栓和抗磷脂综合征的年轻男性发生急性心肌梗死。

Acute myocardial infarction in a young man with large left ventricular thrombus and the antiphospholipid syndrome.

作者信息

Ayan Mohamed, Alshebani Yazeid, Tantoush Hamza, Salih Mohsin, Abusnina Waiel, Khaddr Mansour, Smer Aiman

机构信息

Department of Cardiovascular Medicine, University of Arkansas for Medical SciencesLittle RockArkansas.

Department of Cardiovascular Medicine, CHI Health, Creighton University School of MedicineOmahaNebraska.

出版信息

Proc (Bayl Univ Med Cent). 2018 Nov 13;32(1):110-112. doi: 10.1080/08998280.2018.1503479. eCollection 2019 Jan.

DOI:10.1080/08998280.2018.1503479
PMID:30956601
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6442880/
Abstract

Antiphospholipid syndrome is an autoimmune disorder that presents clinically with venous and/or arterial thrombosis and can affect any organ. Coronary artery involvement and left ventricular thrombus are rare presentations. We report the case of a 23-year-old male smoker with a strong family history of premature coronary artery disease who presented with acute anterolateral ST elevation myocardial infarction and large left ventricular thrombus. He was treated with primary percutaneous coronary intervention with thrombectomy without stenting. He was later diagnosed with antiphospholipid syndrome.

摘要

抗磷脂综合征是一种自身免疫性疾病，临床上表现为静脉和/或动脉血栓形成，可累及任何器官。冠状动脉受累和左心室血栓形成较为罕见。我们报告一例23岁男性吸烟者，有早发冠状动脉疾病的家族史，表现为急性前侧壁ST段抬高型心肌梗死和巨大左心室血栓。他接受了未植入支架的血栓切除术的直接经皮冠状动脉介入治疗。他后来被诊断为抗磷脂综合征。