Hoang Joseph T, Weissenborn Matthew R, Spigel Joseph J, Welch Brian J, Grossman Stanley J
Department of Medicine, Texas A&M College of MedicineDallasTexas.
Department of Radiology, Baylor University Medical Center at DallasDallasTexas.
Proc (Bayl Univ Med Cent). 2019 Feb 6;32(1):140-142. doi: 10.1080/08998280.2018.1519496. eCollection 2019 Jan.
Radioactive iodine I-131 whole-body scintigraphy is used to monitor thyroid cancer metastases after total thyroidectomy. We present a case of a woman who was diagnosed with papillary thyroid cancer and underwent a total thyroidectomy. I-131 scintigraphy revealed abnormal accumulation of radioactive iodine in the right breast causing concern for thyroid cancer metastasis. Mammographic studies confirmed that the abnormal radiotracer accumulation was due to fat necrosis in the breast. I-131 uptake in fat necrosis is a poorly understood process that is not clearly defined in the literature. This case highlights that false-positive uptake of I-131 can mimic metastases of thyroid carcinoma.
放射性碘I-131全身闪烁扫描用于监测甲状腺癌全切除术后的转移情况。我们报告一例女性患者，她被诊断为乳头状甲状腺癌并接受了全甲状腺切除术。I-131闪烁扫描显示右乳放射性碘异常聚集，引起了对甲状腺癌转移的担忧。乳房X线摄影研究证实，放射性示踪剂异常聚集是由于乳腺脂肪坏死所致。脂肪坏死中I-131摄取是一个了解甚少的过程，文献中尚无明确界定。该病例强调I-131的假阳性摄取可模拟甲状腺癌转移。
