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肯尼亚五家地区医院收治儿童的呼吸道合胞病毒感染率:一项横断面研究。

Respiratory syncytial virus prevalence in children admitted to five Kenyan district hospitals: a cross-sectional study.

作者信息

Le Geyt Jacqueline, Hauck Stephanie, Lee Mark, Mackintosh Jennifer, Slater Jessica, Razon Duke, Williams Bhanu

机构信息

Paediatric Emergency Department, Royal Alexandra Children's Hospital, Brighton, UK.

Global Links Volunteer, Royal College of Paediatrics and Child Health, London, UK.

出版信息

BMJ Paediatr Open. 2019 Mar 4;3(1):e000409. doi: 10.1136/bmjpo-2018-000409. eCollection 2019.

Abstract

Acute respiratory infections (ARIs) are a leading cause of under-five mortality globally. In Kenya, the reported prevalence of respiratory syncytial virus (RSV) infections in single-centre studies has varied widely. Our study sought to determine the prevalence of RSV infection in children admitted with ARI fulfilling the WHO criteria for bronchiolitis. This was a prospective cross-sectional prevalence study in five hospitals across central and highland Kenya from April to June 2015. Two hundred and thirty-four participants were enrolled. The overall RSV positive rate was 8.1%, which is lower than in previous Kenyan studies. RSV-positive cases were on average 5 months younger than RSV-negative cases.

摘要

急性呼吸道感染(ARIs)是全球五岁以下儿童死亡的主要原因。在肯尼亚,单中心研究报告的呼吸道合胞病毒(RSV)感染患病率差异很大。我们的研究旨在确定符合世界卫生组织毛细支气管炎标准的ARI住院儿童中RSV感染的患病率。这是一项于2015年4月至6月在肯尼亚中部和高地的五家医院进行的前瞻性横断面患病率研究。共招募了234名参与者。RSV总体阳性率为8.1%,低于肯尼亚以往的研究。RSV阳性病例的平均年龄比RSV阴性病例小5个月。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b4c/6422239/f0ef6169e950/bmjpo-2018-000409f01.jpg

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