Lifshitz S, Railsback L D, Buchsbaum H J
Obstet Gynecol. 1978 Oct;52(4):476-80.
Fourteen patients with advanced localized gynecologic cancer were treated with 44 courses of intraarterial pelvic infusion chemotherapy. All patients received methotrexate with folinic acid rescue; 9 patients also received vincristine. Tumor regression was observed in 3 of 14 patients (21.4%). In 5 patients there were major complications related to 28 intraarterial catheter placements. Two patients developed leukopenia following chemotherapy. The value of intraarterial infusion chemotherapy in gynecologic cancer is limited. Its use in gynecologic oncology is discussed.
14例晚期局限性妇科癌症患者接受了44个疗程的盆腔动脉内灌注化疗。所有患者均接受甲氨蝶呤并辅以亚叶酸解救；9例患者还接受了长春新碱治疗。14例患者中有3例（21.4%）观察到肿瘤消退。5例患者出现与28次动脉内导管置入相关的严重并发症。2例患者化疗后出现白细胞减少。盆腔动脉内灌注化疗在妇科癌症中的价值有限。本文讨论了其在妇科肿瘤学中的应用。
