Lu Lin, Luo Chenguang, Peng Hui, Jiang Huanfeng, Lei Ming, Yin Biaolin
Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering , South China University of Technology , Guangzhou 510640 , People's Republic of China.
State Key Laboratory of Chemical Resource Engineering, College of Science , Beijing University of Chemical Technology , Beijing 100029 , China.
Org Lett. 2019 Apr 19;21(8):2602-2605. doi: 10.1021/acs.orglett.9b00573. Epub 2019 Apr 8.
A variety of structurally novel polycyclic sulfonyl indolines have been synthesized via FeCl-catalyzed or UV-driven intramolecular formal [2 + 2 + 1] dearomatizing cyclization reactions of N-(1 H-indol-3-yl)methyl)propiolamides with NaHSO in an aqueous medium. The reactions involve the formation of one C-C bond and two C-S bonds in a single step.
通过在水介质中，用氯化铁催化或紫外线驱动N-（1H-吲哚-3-基）甲基丙炔酰胺与亚硫酸氢钠进行分子内形式上的[2 + 2 + 1]脱芳构化环化反应，合成了多种结构新颖的多环磺酰基吲哚啉。这些反应一步形成一个碳-碳键和两个碳-硫键。
