Department of Obstetrics and Gynaecology, Fondazione Policlinico Universitario 'A. Gemelli' IRCCS, Rome, Italy.
Università Cattolica del Sacro Cuore, Rome, Italy.
J Matern Fetal Neonatal Med. 2021 Jan;34(2):223-230. doi: 10.1080/14767058.2019.1605592. Epub 2019 Apr 22.
In the last decades, childbearing has moved to higher ages, displaying adverse outcomes related to advanced maternal age at birth. Accordingly, the aim was to perform a cost analysis in women admitted for birth assistance and segregated by age classes (<20, 20-24, 25-29, 30-34, 35-39, 40-45, and ≥45 years). A total of 18,093 admitted for assistance at delivery in a 5-year period (2012-2016) were included in the analysis. Costs for obstetric complications in vaginal delivery (VD) and cesarean section (CS), based on hospital discharge report from the local health care system, were calculated by using the "diagnosis-related group" (DRG) approach. An overall economic cost due to clinical assistance at delivery of €42.663.481 was computed. A global rate of 59.6% of vaginal deliveries (VD) and 40.4% of cesarean section (CS) was assessed. Among of all maternal age classes, women attributable to classes 30-34 and 35-39 years reached a rate of 62.8%, while values of 24.2 and 13% were observed for those under 30 and over 40 years of age, respectively. A significant increasing trend in terms of maternal stay duration was found across all age groups (from 4.7 to 5.4 days, < .05), as well as nonspecific delivery costs (from €2.222.49 to €2.401.29, < .05). Uncomplicated VD decreased across the groups, until to halve between two extreme maternal age groups (38.8 versus 18.6%, < .05), while a three-fold risk of CS complications was calculated in women over 45 years-old in comparison with those under 20 years of age (4.2 versus 13.9, < .05), although not significantly different in the cost analysis between two extreme age groups. Increases in maternal age at delivery are associated with higher healthcare costs, driven largely by additional complication rates, irrespective of the delivery mode.
在过去的几十年中,生育年龄已经推迟到更高的年龄,因此与生育时的高龄产妇相关的不良结局有所增加。因此,目的是对因分娩而住院的女性进行成本分析,并根据年龄分为不同的类别(<20 岁、20-24 岁、25-29 岁、30-34 岁、35-39 岁、40-45 岁和≥45 岁)。在 5 年期间(2012-2016 年),共纳入了 18093 名因分娩而住院的患者。根据当地卫生保健系统的住院报告,使用“诊断相关组”(DRG)方法计算阴道分娩(VD)和剖宫产(CS)的产科并发症成本。计算得出的分娩临床辅助总经济成本为 42663481 欧元。评估了所有产妇年龄组的总体分娩率,其中 59.6%为阴道分娩(VD),40.4%为剖宫产(CS)。在所有产妇年龄组中,30-34 岁和 35-39 岁的产妇比例最高,达到 62.8%,而 30 岁以下和 40 岁以上的产妇比例分别为 24.2%和 13%。随着产妇年龄的增长,产妇的住院时间(从 4.7 天延长至 5.4 天,<.05)和非特异性分娩费用(从 2.22249 欧元增加至 2.40129 欧元,<.05)也呈显著增加趋势。在各个年龄组中,无并发症的 VD 分娩率逐渐降低,在两个极端产妇年龄组中降低了一半(38.8%比 18.6%,<.05),而 45 岁以上的产妇 CS 并发症风险是 20 岁以下产妇的三倍(4.2%比 13.9%,<.05),但在两个极端年龄组之间,成本分析中差异无统计学意义。分娩时产妇年龄的增加与更高的医疗保健成本相关,主要是由于并发症发生率的增加,而与分娩方式无关。