Suppr超能文献

[儿童癫痫发作:分类、诊断、治疗]

[Epileptic seizures in childhood: classification, diagnosis, therapy].

作者信息

Stögmann W

出版信息

Padiatr Padol. 1986;21(3):303-16.

PMID:3095771
Abstract

This is a review about epilepsies of childhood dealing with the elementary principles in classification, diagnosis and treatment. In each case of a patient suffering with epilepsy 3 diagnoses have to be made: the diagnosis of the seizure-type, the diagnosis of the epilepsy-type, the diagnosis of the etiology. The seizure-type has to be diagnosed as generalized (e.g. grand mal, absence seizure) or partial (simple or complex) which can be obtained from the clinical picture and EEG. The classification of seizures is different from the classification of epilepsies: recurrent seizures, only a single type or more types in the same patient, make the diagnosis of the epilepsy-type. The etiologic diagnosis is often not possible to make and requires careful judgment in the use of special procedures; however, the diagnosis of the seizure-type includes their etiology in as much as, for example, awake-grand mal and absence seizures can be classified as idiopathic resp. sleep-grand mal and partial seizures as symptomatic. The most essential principle for the treatment of epilepsies is: the seizures diagnosis determines the appropriate therapy. The drugs of choice for partial seizures and most cases with grand mal are phenytoin and/or carbamazepine; absence seizures and benign myoclonic seizures highly respond to valproate; atonic seizures are most resistant to therapy. To make an effective treatment you have to know the dose, the therapeutic plasma drug level, the drug's half life and the side-effects. The aim of epilepsy-treatment has to be: avoidance of seizures without side-effects.

摘要

这是一篇关于儿童癫痫的综述,涉及分类、诊断和治疗的基本原理。对于每一位癫痫患者,都必须做出三种诊断:发作类型的诊断、癫痫类型的诊断、病因诊断。发作类型必须诊断为全身性发作(如大发作、失神发作)或部分性发作(简单性或复杂性),这可从临床表现和脑电图得出。发作的分类不同于癫痫的分类:反复发作,在同一患者中为单一类型或多种类型,构成癫痫类型的诊断。病因诊断往往无法做出,需要在使用特殊检查时仔细判断;然而,发作类型的诊断包括其病因,例如,清醒大发作和失神发作可归类为特发性,而睡眠大发作和部分性发作归类为症状性。癫痫治疗的最基本原则是:发作诊断决定适当的治疗方法。部分性发作和大多数大发作病例的首选药物是苯妥英钠和/或卡马西平;失神发作和良性肌阵挛发作对丙戊酸盐高度敏感;失张力发作对治疗最具抗性。要进行有效的治疗,必须了解剂量、治疗性血浆药物水平、药物半衰期和副作用。癫痫治疗的目标必须是:避免发作且无副作用。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验