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随机对照试验比较叙事暴露疗法与以当下为中心疗法治疗老年创伤后应激障碍患者。

Randomised controlled trial comparing narrative exposure therapy with present-centred therapy for older patients with post-traumatic stress disorder.

机构信息

Psychotherapist and Researcher,Foundation Centrum '45; and Arq Psychotrauma Expert Group,the Netherlands.

Psychotherapist,Foundation Centrum '45;Arq Psychotrauma Expert Group; andAssistant Professor,Department of Clinical Psychology,Utrecht University,the Netherlands.

出版信息

Br J Psychiatry. 2019 Jun;214(6):369-377. doi: 10.1192/bjp.2019.59. Epub 2019 Apr 8.

Abstract

BACKGROUND

Evidence-based treatment and age-specific services are required to address the needs of trauma-affected older populations. Narrative exposure therapy (NET) may present an appropriate treatment approach for this population since it provides prolonged exposure in a lifespan perspective. As yet, however, no trial on this intervention has been conducted with older adults from Western Europe.AimsExamining the efficacy of NET in a sample of older adults.

METHOD

Out-patients with post-traumatic stress disorder (PTSD), aged 55 years and over, were randomly assigned to either 11 sessions of NET (n = 18) or 11 sessions of present-centred therapy (PCT) (n = 15) and assessed on the Clinician-Administered PTSD Scale (CAPS) pre-treatment, post-treatment and at follow-up. Total scores as well as symptom scores (re-experience, avoidance and hyperarousal) were evaluated.

RESULTS

Using a piecewise mixed-effects growth model, at post-treatment a medium between-treatment effect size for CAPS total score (Cohen's d = 0.44) was found, favouring PCT. At follow-up, however, the between-treatment differences were non-significant. Drop-out rates were low (NET 6.7%, PCT 14.3%) and no participant dropped out of the study because of increased distress.

CONCLUSIONS

Both NET and PCT appear to be safe and efficacious treatments with older adults: PCT is non-intrusive and NET allows for imaginal exposure in a lifespan perspective. By selectively providing these approaches in clinical practice, patient matching can be optimised.Declaration of interestNone.

摘要

背景

为满足创伤后老年人群的需求,需要提供循证治疗和针对特定年龄的服务。叙事暴露疗法(NET)可能是一种适合该人群的治疗方法,因为它提供了从生命历程角度进行的延长暴露。然而,迄今为止,尚未针对来自西欧的老年人开展过该干预措施的试验。

目的

在老年人样本中检验 NET 的疗效。

方法

将患有创伤后应激障碍(PTSD)且年龄在 55 岁及以上的门诊患者随机分配至 NET(n=18)或以当下为中心疗法(PCT)(n=15)组,并在治疗前、治疗后和随访时使用临床医生管理 PTSD 量表(CAPS)进行评估。评估总分以及症状评分(再体验、回避和过度警觉)。

结果

使用分段混合效应增长模型,在治疗后发现 CAPS 总分的中等治疗间效应大小(Cohen's d=0.44),有利于 PCT。然而,在随访时,治疗间差异不显著。脱落率较低(NET 为 6.7%,PCT 为 14.3%),且没有参与者因病情加重而退出研究。

结论

NET 和 PCT 似乎对老年人都是安全且有效的治疗方法:PCT 是非侵入性的,而 NET 允许在生命历程角度进行想象暴露。通过在临床实践中选择性地提供这些方法,可以优化患者匹配。

利益声明

无。

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