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经尿道中段吊带修补术后持续性术后症状的手术结果和危险因素的回顾性分析。

A Retrospective Analysis of Surgical Outcomes and Risk Factors for Persistent Postoperative Symptoms Following Synthetic Mid Urethral Sling Revision.

机构信息

Michigan Medicine, University of Michigan , Ann Arbor , Michigan.

出版信息

J Urol. 2019 Aug;202(2):339-346. doi: 10.1097/JU.0000000000000246. Epub 2019 Jul 8.

Abstract

PURPOSE

The purpose of our study was to describe the symptom profile of patients who presented to a tertiary care hospital for sling revision, define the efficacy of sling removal/revision in alleviating symptoms and identify what factors, if any, contribute to favorable surgical outcomes.

MATERIALS AND METHODS

We retrospectively reviewed the records of patients who underwent revision of a synthetic mid urethral sling at our institution between 2004 and 2016. Patients with a history of vaginal mesh for pelvic organ prolapse were excluded from analysis. The outcomes assessed were the AUASI (American Urological Association Symptom Index) score, the M-ISI (Michigan Incontinence Symptom Index) score, pad use, post-void residual urine volume, examination findings and subjective improvement.

RESULTS

A total of 430 patients met study inclusion criteria, of whom 182, 172 and 40 received a transobturator tape, a retropubic mid urethral sling and a mini-sling, respectively. Patients presented with 4 primary complaints, including mesh exposure or erosion, pain or dyspareunia, incontinence and/or bladder outlet obstruction. Of the patients 77% presented with at least 2 categories of symptoms. Average followup was 15 months. Postoperatively the AUASI score decreased from 19.0 to 14.7 (p <0.001) and the bother score decreased from 5.0 to 3.4 (p <0.001). The M-ISI also improved from total and bother scores of 15.7 and 4.4 to a postoperative average of 13.2 and 3.1 (p = 0.002 and <0.001, respectively). During this time approximately 40% of patients who presented with pain had persistent postoperative discomfort, in 20% with obstruction that condition failed to resolve and recurrent mesh complaints developed in 5% with mesh exposure or erosion. On multivariate analysis preoperative narcotic use was a significant risk factor for persistent postoperative pain (OR 6.9).

CONCLUSIONS

Despite complex patient presentations subjective and objective urological symptom measures significantly improve following mid urethral sling revision.

摘要

目的

我们的研究目的是描述因吊带修复而到三级护理医院就诊的患者的症状谱,定义吊带去除/修复缓解症状的效果,并确定任何可能导致手术结果良好的因素。

材料与方法

我们回顾性分析了 2004 年至 2016 年期间在我院接受合成中尿道吊带修复的患者的记录。有阴道网片治疗盆腔器官脱垂病史的患者被排除在分析之外。评估的结果包括 AUASI(美国泌尿协会症状指数)评分、M-ISI(密歇根尿失禁症状指数)评分、垫使用、残余尿量、检查结果和主观改善。

结果

共有 430 名患者符合研究纳入标准,其中 182、172 和 40 名患者分别接受了经闭孔吊带、耻骨后中尿道吊带和迷你吊带。患者有 4 种主要抱怨,包括网片暴露或侵蚀、疼痛或性交困难、尿失禁和/或膀胱出口梗阻。其中 77%的患者至少有 2 种症状。平均随访时间为 15 个月。术后 AUASI 评分从 19.0 降至 14.7(p<0.001),困扰评分从 5.0 降至 3.4(p<0.001)。M-ISI 也从总分和困扰评分 15.7 和 4.4 改善到术后平均 13.2 和 3.1(p=0.002 和<0.001)。在此期间,约 40%有疼痛症状的患者术后仍有持续不适,20%有梗阻症状的患者未得到缓解,5%有网片暴露或侵蚀的患者出现复发性网片抱怨。多变量分析显示,术前使用麻醉剂是术后持续疼痛的显著危险因素(OR 6.9)。

结论

尽管患者的临床表现复杂,但中尿道吊带修复后,主观和客观的泌尿科症状指标明显改善。

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