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[用于切除乳腺癌快速电子放疗的胸壁模具:不同材料的对比测试]

[Chest wall moulages for radiotherapy of resected breast cancer with fast electrons: comparative tests of different materials].

作者信息

Niewald M, Lehmann W, Tkocz H J, Scharding B, Uhlmann U, Schnabel K, Leetz H K

出版信息

Strahlenther Onkol. 1986 Oct;162(10):605-12.

PMID:3095940
Abstract

Irradiation of the thoracic wall with high-speed electrons is one of the standard methods of prophylaxis and therapy of local recurrences and cutaneous metastases of an operated mammary carcinoma. The surface dose, however, is only 85% of the maximum dose, due to the depth dose curve of the electron beams with the preponderantly applied energy of 7MeV. This is a poor value, since most of all recurrences appear near to the surface and so the risk of giving an insufficient dose is involved. The dose distribution could be essentially improved by the use of moulages on the chest. These moulages were made of different materials which were tested and compared with respect to their suitability for radiotherapeutic purposes. The best materials proved to be "Urgo-Plastan" (manufacturer: Holphar, Sulzbach) and "Orthoplast" (manufacturer: Johnson & Johnson, Düsseldorf). Both materials are synthetic substances which after heating can easily be adapted to the body shape and which offer a good stability, little inconvenience for the patient and a relative easy handling. With these moulage materials, the surface dose is increased to 98% ("Urgo-Plastan") and 99% ("Orthoplast") of the maximum dose.

摘要

用高速电子束照射胸壁是预防和治疗手术切除的乳腺癌局部复发和皮肤转移的标准方法之一。然而,由于电子束深度剂量曲线以及主要应用的7MeV能量,表面剂量仅为最大剂量的85%。这一数值不理想,因为大多数复发发生在靠近表面的部位,所以存在给予剂量不足的风险。通过在胸部使用模具可显著改善剂量分布。这些模具由不同材料制成,针对其放射治疗适用性进行了测试和比较。事实证明,最好的材料是“Urgo - Plastan”(制造商:Holphar,苏尔茨巴赫)和“Orthoplast”(制造商:强生公司,杜塞尔多夫)。这两种材料都是合成物质,加热后能轻松贴合身体形状,具有良好的稳定性,给患者带来的不便小,且操作相对容易。使用这些模具材料后,表面剂量可提高到最大剂量的98%(“Urgo - Plastan”)和99%(“Orthoplast”)。

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