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埃塞俄比亚西南部吉马镇40岁及以上成年人房颤的患病率、危险因素及其抗凝需求:一项基于社区的横断面研究。

Prevalence and risk factors for atrial fibrillation and its anticoagulant requirement in adults aged ≥40 in Jimma Town, Southwest Ethiopia: A community based cross-sectional study.

作者信息

Tegene Elsah, Tadesse Iyasu, Markos Yohannes, Gobena Teshome

机构信息

Department of Internal Medicine, Faculty of Medical Sciences, Institute of Health, Jimma University, Jimma, Ethiopia.

Department of Medical Physiology, Faculty of Medical Sciences, Institute of Health, Jimma University, Jimma, Ethiopia.

出版信息

Int J Cardiol Heart Vasc. 2019 Feb 23;22:199-204. doi: 10.1016/j.ijcha.2019.02.003. eCollection 2019 Mar.

Abstract

BACKGROUND

There is no information on the prevalence and incidence of atrial fibrillation in Ethiopia. We aimed to investigate the prevalence, risk factors and anticoagulant requirements of atrial fibrillation in an elderly Jimma population.

METHODS

In a community-based cross-sectional study in 634 adult (≥40 years) Jimma population, we performed cardiovascular health examinations including a 12-lead electrocardiogram to estimate AF prevalence. A standardized questionnaire was used to collect information on medical history, lifestyle and use of medications. Stroke risk stratification was done using CHADS-VASc score. We used logistic regressions to determine the potential risk factors of AF.

RESULTS

The overall prevalence of AF was 4.3%. AF was associated with sex, current smoking, hypertension and BMI. Nineteen out of twenty seven participants with AF were in need of anticoagulation to prevent risk of stroke.

CONCLUSION

The prevalence of AF is high and common risk factors were sex, current smoking, hypertension, and higher BMI in this cohort. More than two-third of study participants with AF were at higher need of oral anticoagulants.

摘要

背景

埃塞俄比亚尚无关于心房颤动患病率和发病率的信息。我们旨在调查吉马老年人群中心房颤动的患病率、危险因素及抗凝需求。

方法

在一项针对634名成年(≥40岁)吉马人群的社区横断面研究中,我们进行了心血管健康检查,包括12导联心电图以评估房颤患病率。使用标准化问卷收集病史、生活方式和用药情况的信息。采用CHADS-VASc评分进行卒中风险分层。我们使用逻辑回归来确定房颤的潜在危险因素。

结果

房颤的总体患病率为4.3%。房颤与性别、当前吸烟、高血压和体重指数有关。27名房颤参与者中有19名需要抗凝以预防卒中风险。

结论

在该队列中,房颤患病率较高,常见危险因素为性别、当前吸烟、高血压和较高的体重指数。超过三分之二的房颤研究参与者急需口服抗凝剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ade7/6437289/b0c87a8d7b81/gr1.jpg

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