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[白化鹌鹑青光眼时初级视觉系统的退变过程]

[Course of the degeneration of the primary visual system in albino quails with glaucoma].

作者信息

Weidner C, Repérant J, Desroches A M, Miceli D, Rio J P

出版信息

C R Acad Sci III. 1986;303(10):397-402.

PMID:3096501
Abstract

In the quail, a sex-linked albino mutation is associated with buphthalmic glaucoma. This progressive disorder is detectable 3 to 6 months after hatching. Its development leads to a degeneration of retinal projection according to a relatively orderly sequence progressing from the tegmentum to the tectum and from the pretectum to the thalamus. We suggest that the degeneration of visual axons might be produced by mechanical compression resulting from an increase in intraocular pressure.

摘要

在鹌鹑中,一种性连锁白化突变与牛眼性青光眼有关。这种进行性疾病在孵化后3至6个月可检测到。其发展导致视网膜投射按照从被盖到顶盖以及从前顶盖到丘脑的相对有序顺序发生退化。我们认为视觉轴突的退化可能是由眼内压升高导致的机械压迫引起的。

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