青春期前女孩的卵巢黏液性癌伴壁层癌肉瘤成分
Ovarian Mucinous Carcinoma with Mural Carcinosarcomatous Components in a Prepubertal Girl.
作者信息
Suzuki Kayo, Imada Hiroki, Igarashi Akihiro, Saitou Yoko, Takakura Satoshi
机构信息
Department of Obstetrics and Gynecology, Dokkyo Medical University Saitama Medical Center, Koshigaya, Japan.
Department of Pathology, Dokkyo Medical University, Saitama Medical Center, Koshigaya, Japan.
出版信息
J Pediatr Adolesc Gynecol. 2019 Aug;32(4):436-439. doi: 10.1016/j.jpag.2019.04.005. Epub 2019 Apr 6.
BACKGROUND
Epithelial ovarian cancer development before menarche is extremely rare.
CASE
We report a prepubertal girl who developed ovarian mucinous carcinoma with mural carcinosarcomatous components.
SUMMARY AND CONCLUSION
Magnetic resonance imaging showed a polycystic mass with solid components. The left adnexa was removed. Histological analysis revealed a mucinous tumor with mural carcinosarcomatous components. Three weeks later, ascites and peritoneal metastasis were detected. The patient received a combination therapy of paclitaxel with carboplatin. After 4 chemotherapy cycles the right adnexa, uterus, partial omentum, and pelvic peritoneum were removed. Four additional paclitaxel/carboplatin therapy cycles were administered. She remains free from recurrence after 29 months. To our knowledge, this is the first report of ovarian mucinous carcinoma with mural carcinosarcomatous components in a prepubertal girl.
背景
初潮前发生上皮性卵巢癌极为罕见。
病例
我们报告一名青春期前女孩，其发生了具有壁层癌肉瘤成分的卵巢黏液性癌。
总结与结论
磁共振成像显示一个具有实性成分的多囊性肿物。切除了左侧附件。组织学分析显示为一个具有壁层癌肉瘤成分的黏液性肿瘤。三周后，检测到腹水和腹膜转移。患者接受了紫杉醇联合卡铂的治疗。4个化疗周期后，切除了右侧附件、子宫、部分大网膜和盆腔腹膜。又进行了4个紫杉醇/卡铂治疗周期。29个月后她仍无复发。据我们所知，这是青春期前女孩发生具有壁层癌肉瘤成分的卵巢黏液性癌的首例报告。
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