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扶正化瘀方防治慢性肝病的作用及机制。

The effect and mechanisms of Fuzheng Huayu formula against chronic liver diseases.

机构信息

Institute of Liver Diseases, Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China; Shanghai Key Laboratory of Traditional Chinese Medicine, Shanghai, 201203, China.

Institute of Liver Diseases, Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China; Shanghai Key Laboratory of Traditional Chinese Medicine, Shanghai, 201203, China; E-Institute of Shanghai Municipal Education Commission Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.

出版信息

Biomed Pharmacother. 2019 Jun;114:108846. doi: 10.1016/j.biopha.2019.108846. Epub 2019 Apr 7.

Abstract

Fuzheng Huayu formula (FZHY) is a traditional Chinese medicine formula composed of Radix Salvia Miltiorrhizae, Cordyceps, Semen Persicae, Gynostemma Pentaphyllammak, Pollen Pini, Fructus Schisandrae Chinensis that is used to treat chronic liver diseases in China. We here describe the pharmacological actions of FZHY in this review. We also describe and provide updates on recent advances in the medical applications and the basic research of mechanisms of FZHY formula. FZHY has been shown to have no serious adverse reactions and exerts antifibrotic effects through targeting more than one molecule.

摘要

扶正化瘀方(FZHY)是一种由丹参、虫草、桃仁、绞股蓝、松花粉和五味子组成的中药方剂,用于治疗中国的慢性肝病。在这篇综述中,我们描述了 FZHY 的药理作用。我们还描述并提供了 FZHY 方剂在医学应用和机制基础研究方面的最新进展。研究表明,FZHY 无严重不良反应,通过靶向多个分子发挥抗纤维化作用。

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