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母体贫血与妊娠结局:基于人群的研究。

Maternal anemia and pregnancy outcomes: a population-based study.

机构信息

Department of Pediatrics, University of California San Francisco, San Francisco, California, USA.

Department of Pediatrics, University of California San Diego, La Jolla, California, USA.

出版信息

J Perinatol. 2019 Jul;39(7):911-919. doi: 10.1038/s41372-019-0375-0. Epub 2019 Apr 9.

Abstract

OBJECTIVE

This study aims to describe adverse maternal and neonatal outcomes in women diagnosed with anemia in pregnancy.

STUDY DESIGN

This was a retrospective cohort study of California live births from 2007-2012, linked to maternal and infant hospital discharge records. Relative risks of adverse maternal and neonatal outcomes were calculated for women with and without anemia.

RESULTS

Anemic mothers were more likely to be diagnosed with hypertension, diabetes, placental abruption, or chorioamnionitis, or require a blood transfusion or admission to the intensive care unit (aRRs 1.2-6.8). Infants born to anemic mothers were more likely to be born preterm (8.9% versus 6.5%), but not more likely to suffer morbidities associated with prematurity.

CONCLUSION

In a population-based study, the diagnosis of anemia in pregnancy carries a higher risk of peri-partum, intra-partum, and post-partum complications for the mother, and a higher risk of preterm birth for the infant.

摘要

目的

本研究旨在描述妊娠期间诊断为贫血的产妇和新生儿的不良结局。

研究设计

这是一项回顾性队列研究,纳入了 2007 年至 2012 年加利福尼亚州的活产儿,并与产妇和婴儿住院记录相关联。对有和无贫血的产妇和新生儿不良结局的相对风险进行了计算。

结果

贫血产妇更有可能被诊断为高血压、糖尿病、胎盘早剥或绒毛膜羊膜炎,或需要输血或入住重症监护病房(校正相对风险 1.2-6.8)。贫血产妇所生婴儿更有可能早产(8.9% 比 6.5%),但与早产相关的并发症并不更常见。

结论

在一项基于人群的研究中,妊娠期间诊断为贫血会增加产妇围产期、产时和产后并发症的风险,以及婴儿早产的风险。

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