墨西哥北部某城市女性性工作者中通过聚合酶链反应诊断出的感染患病率。

Prevalence of Infection Diagnosed by Polymerase Chain Reaction in Female Sex Workers in a Northern Mexican City.

作者信息

Sánchez-Anguiano Luis Francisco, Velázquez-Hernández Nadia, Guerra-Infante Fernando Martín, Aguilar-Durán Marisela, Pérez-Álamos Alma Rosa, Estrada-Martínez Sergio, Navarrete-Flores José Antonio, Sandoval-Carrillo Ada Agustina, Antuna-Salcido Elizabeth Irasema, Hernández-Tinoco Jesús, Alvarado-Esquivel Cosme

机构信息

Institute for Scientific Research "Dr. Roberto Rivera-Damm ", Juárez University of Durango State, Avenida Universidad S/N, 34000 Durango, Mexico.

Departamento de Infectología, Laboratorio de Virología del Instituto Nacional de Perinatología, Departamento de Microbiología de la Escuela Nacional de Ciencias Biólogicas, Instituto Politécnico Nacional, D.F México.

出版信息

Eur J Microbiol Immunol (Bp). 2019 Feb 2;9(1):5-8. doi: 10.1556/1886.2018.00034. eCollection 2019 Mar 18.

DOI:10.1556/1886.2018.00034

PMID:30967969

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6444802/

Abstract

PURPOSE

We aimed to determine the association between infection and female sex work, and the association between sociodemographic, obstetric, and behavioral characteristics of female sex workers and infection.

METHODS

Through a case-control study design, we studied 201 female sex workers and 201 age-matched women without sex work in Durango City, Mexico. DNA was detected in cervical swab samples using polymerase chain reaction.

RESULTS

DNA was detected in 32 (15.9%) of the 201 cases and in 6 (3.0%) of the 201 controls (odds ratio [OR] = 6.15; 95% confidence interval [CI]: 2.5-15.0; < 0.001). The frequency of infection with in female sex workers did not vary ( > 0.05) regardless of the history of pregnancies, deliveries, cesarean sections, or miscarriages. Regression analysis of the behavioral characteristics showed that infection with was associated only with consumption of alcohol (OR = 2.39; 95% CI: 1.0-5.71; = 0.04). Conclusions: We conclude that infection is associated with female sex work in Durango City, Mexico. This is the first age-matched case-control study on the prevalence of infection in female sex workers in Mexico using detection of DNA in cervical samples.

摘要

目的

我们旨在确定感染与女性性工作之间的关联，以及女性性工作者的社会人口学、产科和行为特征与感染之间的关联。

方法

通过病例对照研究设计，我们对墨西哥杜兰戈市的201名女性性工作者和201名年龄匹配的非性工作女性进行了研究。使用聚合酶链反应在宫颈拭子样本中检测DNA。

结果

201例病例中有32例（15.9%）检测到DNA，201例对照中有6例（3.0%）检测到DNA（优势比[OR]=6.15；95%置信区间[CI]：2.5 - 15.0；P<0.001）。无论怀孕、分娩、剖宫产或流产史如何，女性性工作者中的感染频率均无变化（P>0.05）。行为特征的回归分析表明，感染仅与饮酒有关（OR = 2.39；95% CI：1.0 - 5.71；P = 0.04）。结论：我们得出结论，在墨西哥杜兰戈市，感染与女性性工作有关。这是墨西哥第一项使用宫颈样本中DNA检测对女性性工作者感染患病率进行年龄匹配的病例对照研究。