艰难梭菌高毒力菌株：NAP1/B1/027——简要概述
The Hypervirulent Strain of Clostridium Difficile: NAP1/B1/027 - A Brief Overview.
作者信息
Fatima Rawish, Aziz Muhammad
机构信息
Internal Medicine, Dow University of Health Sciences, Karachi, PAK.
Internal Medicine, University of Kansas Medical Center, Kansas City, USA.
出版信息
Cureus. 2019 Jan 29;11(1):e3977. doi: 10.7759/cureus.3977.
Abstract
Clostridium difficile is a gram-positive bacterium notorious for causing epidemic diarrhea globally with a significant health burden. The pathogen is clinically challenging with increasing antibiotic resistance and recurrence rate. We provide here an in-depth review of one particular strain/ribotype 027, commonly known as NAP1/B1/027 or North American pulsed-field gel electrophoresis type 1, restriction endonuclease analysis type B1, polymerase chain reaction ribotype 027, which has shown a much higher recurrence rate than other strains.
摘要
艰难梭菌是一种革兰氏阳性细菌，因其在全球范围内引发流行性腹泻并造成重大健康负担而臭名昭著。随着抗生素耐药性和复发率的增加，这种病原体在临床上具有挑战性。我们在此对一种特定菌株/核糖型027进行深入综述，该菌株通常被称为NAP1/B1/027或北美脉冲场凝胶电泳1型、限制性内切酶分析B1型、聚合酶链反应核糖型027，其复发率比其他菌株高得多。
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