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新生儿体外膜肺氧合(ECMO)运行期间成功进行全身治疗性低温治疗缺氧缺血性脑病

A Successful Whole Body Therapeutic Hypothermia for Hypoxic Ischemic Encephalopathy During an ECMO Run in a Newborn.

作者信息

Okulu Emel, Erdeve Omer, Pekcici Bahar Bingoler, Kendirli Tanil, Eyileten Zeynep, Atasay Begum, Arsan Saadet

机构信息

Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey.

Division of Developmental Behavioral Pediatrics, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey.

出版信息

Front Pediatr. 2019 Mar 22;7:95. doi: 10.3389/fped.2019.00095. eCollection 2019.

Abstract

Data regarding the safety of using therapeutic hypothermia (TH) with extracorporeal membrane oxygenation (ECMO) in neonates with both hypoxic ischemic encephalopathy (HIE), and respiratory failure are lacking. TH is not associated with an increased incidence of hemostatic complications, but hypothermia may impair coagulation. Herein, we report a case of a newborn who had meconium aspiration syndrome and HIE and underwent both TH and ECMO. He did not have any bleeding or circuit complications, and mortality as short-term outcome along with well-neurodevelopmental outcome.

摘要

关于在患有缺氧缺血性脑病(HIE)和呼吸衰竭的新生儿中使用治疗性低温(TH)联合体外膜肺氧合(ECMO)的安全性数据尚缺乏。TH与止血并发症的发生率增加无关,但低温可能会损害凝血功能。在此,我们报告一例患有胎粪吸入综合征和HIE的新生儿病例,该患儿接受了TH和ECMO治疗。他没有出现任何出血或回路并发症,短期结局为存活,且神经发育良好。

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