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[肉毒杆菌毒素治疗面肌痉挛]

[Therapy of Hemifacial Spasm with Botulinum Toxin].

作者信息

Jost Wolfgang H, Laskawi Rainer, Palmowski-Wolfe Anja, Urban Peter P

机构信息

Parkinson-Klinik Ortenau, Wolfach.

Universitätsmedizin Göttingen, Hals-Nasen-Ohrenklinik, Göttingen.

出版信息

Laryngorhinootologie. 2019 Apr;98(4):247-251. doi: 10.1055/a-0834-4188. Epub 2019 Apr 9.

DOI:10.1055/a-0834-4188
PMID:30968378
Abstract

Hemifacial spasm (HFS) is a frequent disorder characterized by involuntary contractions of those muscles innervated by the facialis nerve on one side of the face. The symptoms can appear as tonic or clonic, intermittent or permanent. Diagnosis is based purely on clinical observation. Differential diagnosis should rely on cranial MRI, which can demonstrate a pathological contact between the nerves and vessels and exclude alternative causation. Often, the symptoms are not marked so that therapy may not be necessary. The therapy of choice is an injection of botulinum toxin to reduce the underlying pathological activity. As an alternative, decompression operation according to Jannetta can be considered, although it is frequently rejected by patients.

摘要

面肌痉挛(HFS)是一种常见疾病,其特征为面部一侧面神经支配的肌肉出现不自主收缩。症状可表现为强直性或阵挛性、间歇性或持续性。诊断完全基于临床观察。鉴别诊断应依靠头颅磁共振成像(MRI),其可显示神经与血管之间的病理性接触并排除其他病因。通常,症状并不明显,因此可能无需治疗。首选治疗方法是注射肉毒杆菌毒素以降低潜在的病理活动。作为替代方案,可考虑根据詹内塔(Jannetta)方法进行减压手术,不过患者常常拒绝这种手术。

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[Therapy of Hemifacial Spasm with Botulinum Toxin].[肉毒杆菌毒素治疗面肌痉挛]
Laryngorhinootologie. 2019 Apr;98(4):247-251. doi: 10.1055/a-0834-4188. Epub 2019 Apr 9.
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[Therapy of Hemifacial Spasm with Botulinum Toxin].[肉毒杆菌毒素治疗面肌痉挛]
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Mapping trends in hemifacial spasm research: bibliometric and visualization-based analyses of the Web of Science Core Collection.绘制面肌痉挛研究趋势图:基于文献计量学和可视化方法对 Web of Science 核心合集的分析。
Neurosurg Rev. 2024 Jan 20;47(1):55. doi: 10.1007/s10143-024-02294-3.
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Rare Diseases of the Salivary Glands and of Facial Nerve.唾液腺和面神经罕见疾病。
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