Ghazaleh Sami, Patel Krunal
University of Toledo
Louisiana State University
The esophagus is a muscular tube for the propulsion of food from the pharynx to the stomach. Histologically, the esophageal wall consists of mucosa, submucosa, and muscularis propria. Esophageal webs and rings are indentations of the esophageal wall that may partially occlude the esophageal lumen. Esophageal webs and rings are usually asymptomatic but can occasionally present with intermittent dysphagia to solids. Esophageal webs are classically associated with Plummer-Vinson syndrome (PVS). It includes the triad of iron-deficiency anemia, postcricoid dysphagia, and upper esophageal webs. Dysphagia is painless and slowly evolving, starting with solid foods and difficulty swallowing liquids after years of onset. Dysphagia becomes symptomatic only when the luminal diameter in the region of the esophageal web becomes less than 12 mm. Esophageal webs and rings are usually asymptomatic but can occasionally present with intermittent dysphagia to the solids. Dysphagia in PVS is generally graded I (occasional dysphagia on taking solids) or grade II (able to swallow only semi-solid diet).
食管是一条肌性管道,用于将食物从咽推进至胃。从组织学上看,食管壁由黏膜、黏膜下层和固有肌层组成。食管蹼和环是食管壁的压迹,可部分阻塞食管腔。食管蹼和环通常无症状,但偶尔可出现间歇性固体食物吞咽困难。食管蹼经典地与普卢默-文森综合征(PVS)相关。它包括缺铁性贫血、环状软骨后吞咽困难和上食管蹼三联征。吞咽困难无痛且进展缓慢,始于固体食物,发病数年之后出现吞咽液体困难。仅当食管蹼区域的管腔直径小于12毫米时,吞咽困难才会出现症状。食管蹼和环通常无症状,但偶尔可出现间歇性固体食物吞咽困难。PVS中的吞咽困难一般分级为I级(进食固体食物时偶尔出现吞咽困难)或II级(仅能吞咽半固体食物)。