Department of Chemistry , University of California , Berkeley , California 94720 , United States.
J Org Chem. 2019 May 3;84(9):5965-5973. doi: 10.1021/acs.joc.9b00631. Epub 2019 Apr 17.
Site-selective late-stage functionalizations of a pyrano[3,2- a]carbazole core related to the murrayamine natural products is reported. Specifically, selective C3 and C6 bromination has been achieved as well as C8 borylation. These functionalizations set the stage for access to a variety of natural products as well as their derivatives.
报道了一种与 Murrayamine 天然产物相关的吡喃并[3,2-a]咔唑核心的选择性晚期功能化。具体来说，已经实现了选择性的 C3 和 C6 溴化以及 C8 硼酸化。这些功能化奠定了获得各种天然产物及其衍生物的基础。
