Asian Liver Center, Stanford University School of Medicine, Palo Alto, California, United States of America.
General Department of Preventive Medicine, Ministry of Health, Hanoi, Vietnam.
PLoS One. 2019 Apr 10;14(4):e0208154. doi: 10.1371/journal.pone.0208154. eCollection 2019.
Infection at birth due to mother-to-child (MTC) transmission is the most common cause of chronic hepatitis B virus (HBV) infection in Vietnam. This study was undertaken to examine the knowledge, attitudes, and practices of pregnant women and mothers in Vietnam concerning HBV prevention and immunization.
A cross-sectional survey was conducted in Quang Ninh and Hoa Binh provinces in 2017. A standardized questionnaire was administered to women when they received care at primary and tertiary maternal health clinics. Multivariate regression was used to identify predictors of HBV knowledge and practices.
Among the 380 women surveyed, 50.3% were pregnant and 49.7% were postpartum. Despite 70.3% of participants reported having received information about HBV during their pregnancy, only 10.8% provided correct answers to all questions regarding HBV transmission routes and preventive measures. Around half of the participants incorrectly believed that HBV is transmitted through sneezing, contaminated water or sharing foods with chronic HBV patients. Although 86.1% of participants believed that HBV vaccination is necessary for infants, only 66.1% responded they were definitely willing to have their own child vaccinated within 24 hours. More than a third of participants expressed concern about having casual contacts or sharing foods with chronic HBV patients. In multivariate analysis, having received information about HBV during their pregnancy was significantly associated with better HBV knowledge score. Delivery at provincial level clinics was a strong predictor for perinatal HBV screening and hepatitis B birth dose administration.
The results highlight the need to prioritize educating pregnant women and mothers in future public health campaigns in order to increase knowledge, reduce misperception, and improve hepatitis B vaccine birth dose coverage in Vietnam.
母婴传播（MTC）导致的出生感染是越南慢性乙型肝炎病毒（HBV）感染的最常见原因。本研究旨在研究越南孕妇和产妇对 HBV 预防和免疫接种的知识、态度和实践。
2017 年在广宁省和华平省进行了一项横断面调查。在初级和三级产妇保健诊所就诊时，向妇女发放标准化问卷。采用多变量回归分析确定 HBV 知识和实践的预测因素。
在所调查的 380 名妇女中，50.3%处于妊娠状态，49.7%处于产后状态。尽管 70.3%的参与者报告在怀孕期间接受了 HBV 相关信息，但只有 10.8%的参与者对 HBV 传播途径和预防措施的所有问题都给出了正确答案。约一半的参与者错误地认为 HBV 通过打喷嚏、受污染的水或与慢性 HBV 患者共同进食传播。尽管 86.1%的参与者认为 HBV 疫苗接种对婴儿是必要的，但只有 66.1%的人表示他们肯定愿意在 24 小时内为自己的孩子接种疫苗。超过三分之一的参与者表示担心与慢性 HBV 患者有偶然接触或共同进食。多变量分析显示，怀孕期间接受过 HBV 相关信息与更好的 HBV 知识评分显著相关。在省级诊所分娩是围产期 HBV 筛查和乙型肝炎疫苗出生剂量接种的强有力预测因素。
研究结果强调，需要在未来的公共卫生运动中优先教育孕妇和产妇，以提高知识水平、减少误解并提高越南乙型肝炎疫苗出生剂量覆盖率。
