Molnar C, Opincariu D, Benedek T, Toma M, Nicolescu C
1st Surgery Clinic, University of Medicine and Pharmacy of Tîrgu Mureş, Tîrgu Mureş, Romania.
TopMed Medical Center, Tîrgu Mureş, Romania.
Braz J Med Biol Res. 2019 Apr 8;52(4):e8330. doi: 10.1590/1414-431X20198330.
We sought to assess clinical characteristics and pattern of collateral network involvement associated with development of truncal (systematized) versus diffuse/non-truncal (non-systematized) varicose veins (VVs) in patients undergoing endovascular laser photothermolysis for chronic venous insufficiency (CVI). Secondly, we aimed to assess whether the type of VVs influenced the procedural complications of endovascular laser therapy. A total of 508 patients with hydrostatic VVs of the lower limbs who underwent endovenous laser treatment were included, out of which 84.1% (n=427) had truncal VVs (group 1) and 15.9% (n=81) had diffuse (non-systematized) VVs (group 2). Patients with truncal varices were significantly older (47.50±12.80 vs 43.15±11.75 years, P=0.004) and those with associated connective tissue disorders were more prone to present diffuse VVs (P=0.004). Patients in group 1 presented a significantly higher number of Cockett 1 (P=0.0017), Cockett 2 (P=0.0137), Sherman (P<0.0001), and Hunter (P=0.0011) perforator veins compared to group 2, who presented a higher incidence of Kosinski perforators (P<0.0001). There were no significant differences regarding postoperative complications: thrombophlebitis (P=0.773), local inflammation (P=0.471), pain (P=0.243), paresthesia (P=1.000), or burning sensation (P=0.632). Patients with more advanced CEAP (clinical, etiologic, anatomic, pathophysiologic) classes were older (P<0.0001), more were males (39.05 vs 27.77%, P=0.0084), more were prone to present ulcers (P<0.0001) and local hyperthermia (P=0.019), and presented for endovenous phlebectomy after a longer time from symptom onset. In patients with CVI, systematized VVs were associated with a more severe clinical status and a distinct anatomical pattern of perforators network compared to non-systematized VVs, which is more common in advanced stages.
我们试图评估接受慢性静脉功能不全(CVI)血管内激光光热疗法的患者中,与躯干型(系统化)和弥漫性/非躯干型(非系统化)静脉曲张(VV)发展相关的临床特征和侧支网络受累模式。其次,我们旨在评估VV的类型是否会影响血管内激光治疗的手术并发症。共有508例接受下肢静脉激光治疗的静水压性VV患者纳入研究,其中84.1%(n = 427)为躯干型VV(第1组),15.9%(n = 81)为弥漫性(非系统化)VV(第2组)。躯干型静脉曲张患者年龄显著更大(47.50±12.80岁 vs 43.15±11.75岁,P = 0.004),且伴有结缔组织疾病的患者更易出现弥漫性VV(P = 0.004)。与第2组相比,第1组患者的Cockett 1(P = 0.0017)、Cockett 2(P = 0.0137)、Sherman(P < 0.0001)和Hunter(P = 0.0011)穿支静脉数量显著更多,而第2组Kosinski穿支静脉的发生率更高(P < 0.0001)。术后并发症方面无显著差异:血栓性静脉炎(P = 0.773)、局部炎症(P = 0.471)、疼痛(P = 0.243)、感觉异常(P = 1.000)或烧灼感(P = 0.632)。CEAP(临床、病因、解剖、病理生理)分级更高的患者年龄更大(P < 0.0001),男性更多(39.05% vs 27.77%,P = 0.0084),更易出现溃疡(P < 0.0001)和局部高温(P = 0.019),且从症状出现到接受静脉剥脱术的时间更长。在CVI患者中,与非系统化VV相比,系统化VV与更严重的临床状态和独特的穿支网络解剖模式相关,非系统化VV在晚期更为常见。