通过硫醇-烯点击反应实现两亲性聚醚-八官能化多面体低聚倍半硅氧烷的简便合成与自组装

Facile Synthesis and Self-Assembly of Amphiphilic Polyether-Octafunctionalized Polyhedral Oligomeric Silsesquioxane via Thiol-Ene Click Reaction.

作者信息

Xia Yong, Ding Sha, Liu Yuejun, Qi Zhengjian

机构信息

Key Laboratory of Advanced Packaging Materials and Technology of Hunan Province, Hunan University of Technology, Zhuzhou 412007, China.

College of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China.

出版信息

Polymers (Basel). 2017 Jun 28;9(7):251. doi: 10.3390/polym9070251.

We demonstrated here a facile and efficient synthesis of polyhedral oligomeric silsesquioxane-based amphiphilic polymer by thiol-ene click chemistry. The properties of polyhedral oligomeric silsesquioxane (POSS)⁻PEG amphiphilic polymers were studied in detail by a combination of ¹H NMR, C NMR, Si NMR FT-IR, GPC, and TG analysis. The newly-designed thiol-ene protocol obtains only anti-Markovnikov addition POSS-based amphiphilic polymers when compared with platinum-catalysed hydrosilylation method. The critical micelle concentration (CMC) of the resulting polymers are in the range of 0.011 to 0.050 mg/mL, and dynamic light scattering (DLS) results revealed that the obtained amphiphilic polymers can self-assemble into nanoparticles in aqueous solutions with a bimodal (two peaks) distribution. Furthermore, the specific polymer showed obvious thermo-sensitive behaviour at 45.5 °C.

我们在此展示了通过硫醇-烯点击化学简便高效地合成基于多面体低聚倍半硅氧烷的两亲聚合物。通过¹H NMR、C NMR、Si NMR、FT-IR、GPC和TG分析相结合的方法，对多面体低聚倍半硅氧烷（POSS）⁻PEG两亲聚合物的性质进行了详细研究。与铂催化的硅氢化方法相比，新设计的硫醇-烯方案仅获得反马氏加成的基于POSS的两亲聚合物。所得聚合物的临界胶束浓度（CMC）在0.011至0.050 mg/mL范围内，动态光散射（DLS）结果表明，所获得的两亲聚合物在水溶液中可自组装成具有双峰（两个峰）分布的纳米颗粒。此外，特定聚合物在45.5 °C时表现出明显的热敏行为。