Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
Department of Data Management and Analysis, Region Västra Götaland, Gothenburg, Sweden.
Int J Stroke. 2019 Dec;14(9):862-870. doi: 10.1177/1747493019840939. Epub 2019 Apr 10.
Time delay from stroke onset to hospital arrival is an important obstacle to recanalization therapy. To increase knowledge about stroke symptoms and potentially reduce delayed hospital arrival, a 27-month national public information campaign was conducted in Sweden.
To assess the effects of a national stroke campaign in Sweden.
This nationwide study included 97,840 patients with acute stroke, admitted to hospital and registered in the Swedish Stroke Register from 1 October 2010 to 31 December 2014 (one year before the campaign started to one year after the campaign ended). End points were (1) proportion of patients arriving at hospital within 3 h of stroke onset and (2) the proportion < 80 years of age receiving recanalization therapy.
During the campaign, both the proportion of patients arriving at hospital within 3 h (p < 0.05) and the proportion receiving recanalization therapy (p < 0.001) increased. These proportions remained stable the year after the campaign, and no significant improvements with respect to the two end points were observed during the year preceding the campaign. In a multivariable logistic regression model comparing the last year of the campaign with the year preceding the campaign, the odds ratio of arriving at hospital within 3 h was 1.05 (95% confidence interval (CI): 1.00-1.09) and that of receiving recanalization was 1.34 (95% CI: 1.24-1.46).
The Swedish National Stroke Campaign was associated with a sustained increase in the proportion of patients receiving recanalization therapy and a small but significant improvement in the proportion arriving at hospital within 3 h.
从卒中发病到医院到达的时间延迟是再通治疗的一个重要障碍。为了提高对卒中症状的认识，并有可能减少延迟到院，在瑞典开展了一项为期 27 个月的全国性公众信息宣传活动。
评估瑞典全国卒中宣传活动的效果。
这项全国性研究纳入了 2010 年 10 月 1 日至 2014 年 12 月 31 日期间因急性卒中住院并在瑞典卒中登记处登记的 97840 例患者（在宣传活动开始前一年至结束后一年）。终点为（1）发病后 3 小时内到达医院的患者比例和（2）<80 岁接受再通治疗的患者比例。
在宣传活动期间，到达医院 3 小时内的患者比例（p<0.05）和接受再通治疗的患者比例（p<0.001）均升高。在宣传活动结束后的一年中，这两个比例保持稳定，且在宣传活动前一年并未观察到两个终点的显著改善。在比较宣传活动最后一年与前一年的多变量逻辑回归模型中，3 小时内到达医院的比值比为 1.05（95%置信区间：1.00-1.09），接受再通治疗的比值比为 1.34（95%置信区间：1.24-1.46）。
瑞典全国卒中宣传活动与接受再通治疗的患者比例持续增加以及 3 小时内到达医院的患者比例略有显著改善相关。
