Faculty of Health and Medical Sciences, Institute of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Neurovascular Research Unit, Herlev Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Brain Behav. 2021 Aug;11(8):e2225. doi: 10.1002/brb3.2225. Epub 2021 Jun 4.
Timely evaluation and initiation of treatment is the key for improving stroke outcomes, although minimizing the time from symptom onset to the first contact with healthcare professionals remains a challenge. We aimed to identify patient-related factors associated with early hospital arrival.
In this cross-sectional survey, we included patients with stroke or transient ischemic attack admitted directly to one of two noncomprehensive stroke units or transferred to the units from comprehensive stroke centers in the Capital Region of Denmark. Patient-reported factors associated with early hospital arrival were analyzed using multivariable logistic regression analysis adjusted for age, sex, education, living arrangement, brain location of the stroke, stroke severity, patient-perceived symptom severity, history of prior stroke, stroke risk factors, and knowledge of stroke symptoms.
In total, 479 patients with acute stroke were included (median age 74 (25th-75th percentile, 64-80), 40% women), of whom 46.4% arrived within 180 min of symptom onset. Factors associated with early hospital arrival were patients or bystanders choosing emergency medical service (EMS) for the first contact with a medical professional (adjusted odds ratio (OR), 3.41; 95% confidence interval, CI [1.57, 7.35]) or the patient's perceived symptom severity above the median score of 25 on a 100-point verbal scale (adjusted OR, 2.44; 95% CI [1.57, 3.82]). Living alone reduced the likelihood of early arrival (adjusted OR, 0.53; 95% CI [0.33, 0.86]).
Only when patients perceived symptoms as severe or when EMS was selected as the first contact, early arrival for stroke treatment was ensured.
及时评估和启动治疗是改善中风预后的关键,尽管将症状发作到首次接触医疗保健专业人员的时间最小化仍然是一个挑战。我们旨在确定与早期医院到达相关的患者相关因素。
在这项横断面调查中,我们纳入了直接入住丹麦首都地区两家非综合卒中单位或从综合卒中中心转至这些单位的卒中或短暂性脑缺血发作患者。使用多变量逻辑回归分析调整年龄、性别、教育、居住安排、中风大脑位置、中风严重程度、患者感知症状严重程度、既往中风史、中风危险因素和中风症状知识等因素,分析与早期医院到达相关的患者报告因素。
共纳入 479 例急性中风患者(中位数年龄 74 岁(25 至 75 百分位数,64-80 岁),40%为女性),其中 46.4%在症状发作后 180 分钟内到达。与早期医院到达相关的因素是患者或旁观者选择紧急医疗服务(EMS)作为与医疗专业人员的首次接触(调整后的优势比(OR),3.41;95%置信区间,CI [1.57, 7.35])或患者感知症状严重程度高于 100 点言语量表的中位数评分 25 分(调整后的 OR,2.44;95%CI [1.57, 3.82])。独居降低了早期到达的可能性(调整后的 OR,0.53;95%CI [0.33, 0.86])。
只有当患者感知症状严重或选择 EMS 作为首次接触时,才能确保早期到达进行中风治疗。