Kwok Christine Y, Ting Yonghan
Department of Diagnostic Radiology, Tan Tock Seng Hospital, Singapore, Singapore.
Am J Case Rep. 2019 Apr 11;20:499-502. doi: 10.12659/AJCR.913327.
BACKGROUND Acute muscular sarcocystosis (AMS) is one of a spectrum of diseases caused by the Sarcocystis parasite which infects humans in regions where it is endemic. Infections present with non-specific signs and symptoms and have been known to occur in clusters. CASE REPORT A 51-year-old Vietnamese male presented to Tan Tock Seng Hospital, Singapore with 3 weeks of fever, urticarial rash, non-productive cough, and lower back pain. He had an extensive travel history prior to presentation. Magnetic resonance imaging (MRI) showed myositis involving the paravertebral and upper thigh muscles. The infection was confirmed on open muscle biopsy and Sarcocystis nesbitti was identified on molecular testing. The patient was treated with prednisone and methotrexate. CONCLUSIONS AMS must be considered in a patient with history of exposure to an endemic area. Diagnosis of the condition and identification of S. nesbitti as the causative organism will help to further study of this particular condition and guide treatment.
背景 急性肌肉肉孢子虫病（AMS）是由肉孢子虫寄生虫引起的一系列疾病之一，在其流行地区可感染人类。感染表现为非特异性体征和症状，且已知会呈聚集性发生。病例报告 一名51岁的越南男性因持续3周的发热、荨麻疹样皮疹、干咳和下背部疼痛就诊于新加坡陈笃生医院。就诊前他有广泛的旅行史。磁共振成像（MRI）显示椎旁和大腿上部肌肉出现肌炎。通过开放性肌肉活检确诊感染，并通过分子检测鉴定出奈氏肉孢子虫。患者接受了泼尼松和甲氨蝶呤治疗。结论 对于有疫区接触史的患者，必须考虑AMS。对该病的诊断以及将奈氏肉孢子虫鉴定为致病生物将有助于对这一特殊疾病的进一步研究并指导治疗。
