Giant cell carcinoma of the pancreas. Report of a case with upper gastrointestinal bleeding diagnosed by endoscopic brush cytology.

A case of upper gastrointestinal bleeding as the first and only manifestation of giant cell carcinoma of the pancreas invading the duodenum is described. The polypoid tumor was visualized during endoscopy. The diagnosis was made by a cytologic brush and confirmed by endoscopic biopsy. The rather uncommon presentation of pancreatic carcinoma and the possibility of establishing the diagnosis by a cytologic brush is discussed.