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维生素D水平与冠状动脉搭桥术后房颤发生率的关系

Relationship between Vitamin D Levels and the Incidence of Post Coronary Artery Bypass Graft Surgery Atrial Fibrillation.

作者信息

Daie Maryam, Hajhossein Talasaz Azita, Karimi Abbasali, Gholami Kheirollah, Salehiomran Abbas, Ariannejad Hamid, Jalali Arash

机构信息

Department of Clinical Pharmacy, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

J Tehran Heart Cent. 2018 Oct;13(4):159-165.

Abstract

Postoperative atrial fibrillation (POAF) is probably a consequence of inflammation. Vitamin D is known for its anti-inflammatory properties. The aim of this study was to evaluate the effects of vitamin D levels on the incidence of POAF. In a prospective cohort study, patients were monitored for the occurrence of POAF during the first 5 days after coronary artery bypass grafting surgery in Tehran Heart Center. Those with concomitant valvular surgeries were excluded. Thereafter, they were divided into 2 groups: with or without POAF. Vitamin D levels were assessed in all the patients. The relationship between the vitamin D level and the incidence of POAF was evaluated and compared between the groups using the Mann-Whitney U test. The study population comprised of 156 patients. The mean age was 62.8±8.6 years, and 105 (67.3%) patients were male. Of the 156 patients, 29 (19%) developed POAF. The median preoperative vitamin D level was 15.3 in the group with POAF and 25.3 in the group without POAF (P=0.07). Our results demonstrated no significant relationship between vitamin D levels and the occurrence of POAF.

摘要

术后房颤(POAF)可能是炎症的结果。维生素D以其抗炎特性而闻名。本研究的目的是评估维生素D水平对POAF发生率的影响。在一项前瞻性队列研究中,对德黑兰心脏中心冠状动脉搭桥手术后前5天内的患者进行POAF发生情况监测。排除同时进行瓣膜手术的患者。此后,将他们分为两组:发生POAF组和未发生POAF组。对所有患者评估维生素D水平。使用曼-惠特尼U检验评估并比较两组之间维生素D水平与POAF发生率的关系。研究人群包括156例患者。平均年龄为62.8±8.6岁,105例(67.3%)患者为男性。在156例患者中,29例(19%)发生了POAF。发生POAF组术前维生素D水平中位数为15.3,未发生POAF组为25.3(P=0.07)。我们的结果表明维生素D水平与POAF的发生之间无显著关系。

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