Tualeka Abdul Rohim, Pathak Yashwant, Wibrata Dwi Ananto, Ilmi Bahrul, Ahsan Ahsan, Rahmawati Pudji, Russeng Syamsiar S, Wahyu Atjo, Maspiyah Maspiyah, Sukarmin Sukarmin
Department of Occupational Health and Safety, Faculty of Public Health, Airlangga University, 60115 Surabaya, East Java, Indonesia.
College of Pharmacy, University of South Florida, 12901 Bruce Blvd., MDC 30 Tampa, FL 33612, USA.
Open Access Maced J Med Sci. 2019 Mar 14;7(5):816-823. doi: 10.3889/oamjms.2019.136. eCollection 2019 Mar 15.
Benzene is a hazardous ingredient for health. Benzene is used as a latex glue solvent in the shoe industry.
The purpose of the study was to analyse the relationship between benzene exposure with trans, trans-muconic acid (t, t-MA) and the blood profile of shoe workers in Romokalisari Surabaya.
The study was a cross-sectional design conducted in the shoe industry in Romokalisari Surabaya with some subjects of 20 shoe workers. Data collection was carried out by measuring benzene levels conducted at 8 measurement points in Surabaya Romokalisari, taking workers' blood, measuring body weight and conducting interviews with respondents. Data were analysed using correlation tests.
The results showed that there was no relationship between benzene levels with t, t-MA (p-value = 0.205), there was no relationship between benzene Risk Quotient (RQ) and t, t-MA (p-value = 0.271) and there was no relationship between the Excess Cancer Risk (ECR) and blood profile of workers in Romokalisari. However, there were some abnormal blood profile parameters due to exposure to benzene although it was small.
It seems another factors such as length of work, nutritional status, duration of exposure, weight, and frequency of exposure have a considerable contribution in the determination of intake of xenobiotic ingredients in the body to cause health effects especially blood profiles.
苯是一种对健康有害的成分。苯在制鞋行业中用作乳胶胶水溶剂。
本研究的目的是分析泗水罗莫卡利萨里制鞋工人的苯暴露与反式，反式粘康酸（t，t-MA）及血液指标之间的关系。
本研究采用横断面设计，在泗水罗莫卡利萨里的制鞋行业中对20名制鞋工人进行研究。通过在泗水罗莫卡利萨里的8个测量点测量苯水平、采集工人血液、测量体重以及对受访者进行访谈来收集数据。使用相关性检验对数据进行分析。
结果表明，苯水平与t，t-MA之间无相关性（p值 = 0.205），苯风险商（RQ）与t，t-MA之间无相关性（p值 = 0.271），罗莫卡利萨里工人的超额癌症风险（ECR）与血液指标之间无相关性。然而，尽管苯暴露量较小，但仍有一些血液指标参数出现异常。
似乎工作时长、营养状况、暴露持续时间、体重和暴露频率等其他因素在决定体内外源性成分摄入量以引起健康影响尤其是血液指标方面有相当大的作用。
