Quaresma Abel B, Kaplan Gilaad G, Kotze Paulo G
aWest Santa Catarina State University (UNOESC), Joaçaba, Brazil bUniversity of Calgary, Calgary, Alberta, Canada cCatholic University of Paraná (PUCPR), Curitiba, Brazil.
Curr Opin Gastroenterol. 2019 Jul;35(4):259-264. doi: 10.1097/MOG.0000000000000534.
Epidemiological studies of inflammatory bowel disease (IBD) in newly industrialized countries are limited, due to a lack of medical surveillance systems and reliable and unified registries and databases. In Brazil, reliable data on the incidence and prevalence of Crohn's disease and ulcerative colitis is scarce. The objective of the present review is to describe in detail the available data on the incidence and prevalence of Crohn's disease and ulcerative colitis in Brazil.
The authors identified the single four population-based studies which refer to incidence and prevalence of IBD in the country (two from São Paulo, one from Espírito Santo and one from the state of Piauí). These studies demonstrate a remarkable growth in the incidence and estimated prevalence of IBD in Brazil, with higher number of cases in more developed regions.
The increase in incidence over time and the higher current prevalence are indicative of a historical progression in relation to the number of IBD patients in our country, similar to what was observed in countries from Asia and approximating those of the northern hemisphere. Epidemiological studies with more accurate methodology are needed in Brazil.
由于缺乏医疗监测系统以及可靠且统一的登记处和数据库,新兴工业化国家炎性肠病(IBD)的流行病学研究有限。在巴西,关于克罗恩病和溃疡性结肠炎发病率及患病率的可靠数据稀缺。本综述的目的是详细描述巴西克罗恩病和溃疡性结肠炎发病率及患病率的现有数据。
作者确定了四项基于人群的研究,这些研究涉及该国IBD的发病率和患病率(两项来自圣保罗,一项来自圣埃斯皮里图州,一项来自皮奥伊州)。这些研究表明,巴西IBD的发病率和估计患病率显著增长,在较发达地区病例数更多。
随着时间推移发病率增加以及当前患病率较高,表明我国IBD患者数量呈历史性增长,类似于亚洲国家所观察到的情况,接近北半球国家。巴西需要采用更精确方法的流行病学研究。