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使用从蛇咬伤受害者获取的供体角膜进行角膜移植的结果。

Outcomes of Corneal Transplantation Using Donor Corneas Retrieved From Snakebite Victims.

作者信息

Donthineni Pragnya Rao, Chaurasia Sunita, Garg Prashant

机构信息

Tej Kohli Cornea Institute, LV Prasad Eye Institute, Hyderabad, Telangana, India.

Ramayamma International Eye Bank, LV Prasad Eye Institute, Hyderabad, Telangana, India.

出版信息

Cornea. 2019 Jul;38(7):836-839. doi: 10.1097/ICO.0000000000001953.

DOI:10.1097/ICO.0000000000001953
PMID:30973408
Abstract

PURPOSE

To report the outcomes of corneal transplantation using donor corneas retrieved from snakebite victims.

METHODS

This study was a retrospective analysis of 30 corneal transplants performed from 2014 to 2016 using donor corneas retrieved from snakebite victims. The details of the donor corneal characteristics and the transplant recipients were collected from the eye bank and the medical records department.

RESULTS

The mean age of the donors was 30.4 ± 17.5 years. The median death-to-preservation time was 3.3 hours [interquartile range: 1.3-5.6 hours]. Ninety percent (27/30) of the corneas were evaluated as optical grade, and 10% (3/30) of the corneas were deemed as therapeutic grade. The mean endothelial cell density on specular microscopy of the donor corneas was 2943 ± 615 cells/mm, and median corneal thickness was 514 μm (interquartile range: 506-520). Seventy-five percent of the corneas transplanted had cleared, with a mean follow-up duration of 1.5 ± 1.0 years (range: 0.4-3.7) years and mean logarithm of the minimum angle of resolution (LogMAR) visual acuity of 0.51 ± 0.27 (range: 0-1.2) at the last follow-up.

CONCLUSIONS

The donor corneas retrieved from snakebite victims are apparently safe and suitable for transplantation, and screening for such donor corneas should include a thorough examination of ocular adnexa to rule out local envenomation before corneal retrieval in addition to the routine evaluation protocol.

摘要

目的

报告使用从蛇咬伤受害者获取的供体角膜进行角膜移植的结果。

方法

本研究是对2014年至2016年使用从蛇咬伤受害者获取的供体角膜进行的30例角膜移植的回顾性分析。从眼库和病历部门收集供体角膜特征及移植受者的详细信息。

结果

供体的平均年龄为30.4±17.5岁。死亡至保存的中位时间为3.3小时[四分位间距:1.3 - 5.6小时]。90%(27/30)的角膜被评估为光学级,10%(3/30)的角膜被视为治疗级。供体角膜镜面显微镜检查的平均内皮细胞密度为2943±615个细胞/mm,角膜中位厚度为514μm(四分位间距:506 - 520)。75%的移植角膜已清除,平均随访时间为1.5±1.0年(范围:0.4 - 3.7年),最后一次随访时最小分辨角对数(LogMAR)视力的平均值为0.51±0.27(范围:0 - 1.2)。

结论

从蛇咬伤受害者获取的供体角膜显然安全且适合移植,除常规评估方案外,对此类供体角膜进行筛查时,在获取角膜前应包括对眼附属器的全面检查以排除局部中毒。

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