Lady Hardinge Medical College, Connaught Place, New Delhi, Delhi, India.
Cornea and Anterior Segment Service, L V Prasad Eye Institute, Bhubaneswar, Odisha, India.
Indian J Ophthalmol. 2021 Dec;69(12):3494-3497. doi: 10.4103/ijo.IJO_8_21.
To analyze the quality of tissues and outcome of corneal transplants from tissues harvested from the donors of organophosphorus poisoning victims.
A retrospective study was carried out on corneas harvested from organophosphorus poisoning victims between January 2016 and December 2018. Details of quality of tissues and outcome following keratoplasty were collected from the eye bank and outpatient records, respectively.
Four hundred and seventy-eight donor corneas were collected from the victims of organophosphorus poisoning during the study period. The mean age of the donor was 38.8 ± 16.5 years. The mean donor-to-preservation time was 6.2 ± 3.2 hours. The mean endothelial cell density on specular microscopy was 2986.5 ± 369.0 cells/mm. Four hundred and twenty-two (88.2%) donor corneas were utilized. Of the 121 corneas utilized at our institute for transplantation, 73 and 48 corneas were for optical and therapeutic/tectonic indications, respectively. Of the 73 optical grafts, 25 patients were lost-to-follow-up and 58.3% (28/48) who came for one-year follow-up were found to be clear.
Donor corneas retrieved from organophosphorus poisoning are safe for transplantation. The postoperative outcome of the tissue utilized from these donors is satisfactory.
分析从有机磷中毒供体中获取的组织的质量和角膜移植的结果。
对 2016 年 1 月至 2018 年 12 月期间从有机磷中毒受害者中采集的角膜进行了回顾性研究。从眼库和门诊记录中分别收集了组织质量和角膜移植后结果的详细信息。
在研究期间，从有机磷中毒受害者中采集了 478 个供体角膜。供体的平均年龄为 38.8 ± 16.5 岁。供体到保存的平均时间为 6.2 ± 3.2 小时。共聚焦显微镜下的平均内皮细胞密度为 2986.5 ± 369.0 个细胞/mm。422 个（88.2%）供体角膜得到利用。在我们研究所，有 121 个角膜用于移植，其中 73 个和 48 个分别用于光学和治疗/修复目的。在 73 个光学移植物中，25 名患者失访，58.3%（28/48）接受一年随访的患者视力清晰。
从有机磷中毒供体中获取的供体角膜可安全用于移植。从这些供体中利用的组织的术后结果令人满意。
