Donaldson R M, Honey M, Sturridge M F, Wright J E, Balcon R
Br Heart J. 1978 Nov;40(11):1200-4. doi: 10.1136/hrt.40.11.1200.
Three hundred and forty-three patients who had aortocoronary bypass graft operations for disabling angina were followed up for from 6 months to 5 years (average 2 years). 80 per cent had multiple grafts and 20 per cent had additional endarterectomy. The overall mortality within one month of operation was 5 per cent, and in those who had vein graft procedures only was 4 per cent. 11 per cent had a postoperative myocardial infarction (6% perioperative) and there were 3 per cent late deaths. At 3 years 90 per cent are surviving. 80 per cent are asymptomatic without treatment. The mean angina grade was 0.3 at the latest follow-up, compared with 2.5 before operation; maximum exercise tolerance was also significantly improved (P less than 0.001). When angina recurred, it did so in 80 per cent of the cases within 12 months of operation and was usually attributable to inadequate revascularisation. Ventricular function as assessed by preoperative ventriculography was the factor most clearly related to survival rate and the early excellent results of coronary bypass operations seem to be maintained up to 5 years. It is, therefore, reasonable to continue to advise operation if only for relief of angina.
343例因严重心绞痛接受主动脉冠状动脉搭桥手术的患者接受了6个月至5年(平均2年)的随访。80%的患者接受了多支血管搭桥,20%的患者还接受了动脉内膜切除术。手术1个月内的总死亡率为5%,仅接受静脉搭桥手术的患者死亡率为4%。11%的患者发生了术后心肌梗死(围手术期为6%),晚期死亡率为3%。3年时,90%的患者存活。80%的患者未经治疗无症状。在最近一次随访时,平均心绞痛分级为0.3,而术前为2.5;最大运动耐量也有显著改善(P<0.001)。心绞痛复发时,80%的病例在术后12个月内复发,通常是由于血管再通不充分。术前心室造影评估的心室功能是与生存率最密切相关的因素,冠状动脉搭桥手术的早期良好效果似乎可以维持5年。因此,仅为缓解心绞痛而建议继续手术是合理的。