Malde Oyvind, Libby Joseph, Moazen Mehran
UCL Mechanical Engineering, University College London, London.
School of Engineering and Computer Science, University of Hull, Hull, UK.
Mol Syndromol. 2019 Feb;10(1-2):74-82. doi: 10.1159/000490833. Epub 2018 Jul 11.
Craniosynostosis is a medical condition caused by the early fusion of the cranial joint. The finite element method (FEM) is a computational technique that can answer a variety of "what if" questions in relation to the biomechanics of this condition. The aim of this study was to review the current literature that has used FEM to investigate the biomechanics of any aspect of craniosynostosis, being its development or its reconstruction. This review highlights that a relatively small number of studies ( = 10) has used FEM to investigate the biomechanics of craniosynostosis. Current studies set a good foundation for the future to take advantage of this method and optimize reconstruction of various forms of craniosynostosis.
颅缝早闭是一种由颅骨关节过早融合引起的医学病症。有限元法（FEM）是一种计算技术，可回答与该病症生物力学相关的各种“如果……会怎样”的问题。本研究的目的是回顾当前使用有限元法研究颅缝早闭任何方面（无论是其发展还是重建）生物力学的文献。该综述强调，相对较少的研究（n = 10）使用有限元法研究颅缝早闭的生物力学。当前的研究为未来利用这种方法并优化各种形式颅缝早闭的重建奠定了良好基础。
