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主动脉瘤患者Tp-Te间期及Tp-Te/Qt比值的评估

Assessment of Tp-Te Interval and Tp-Te/Qt Ratio in Patients with Aortic Aneurysm.

作者信息

Boduroglu Yalcin, Son Osman

机构信息

Department of Cardiology, Ahi Evran University Education and Research Hospital, Kirsehir, Turkey.

Department of Endocrinology, Private Acibadem Hospital, Eskisehir, Turkey.

出版信息

Open Access Maced J Med Sci. 2019 Mar 13;7(6):943-948. doi: 10.3889/oamjms.2019.191. eCollection 2019 Mar 30.

Abstract

BACKGROUND

Arrhythmic disorders in the aortic aneurysm (AA) have been rarely reported.

AIM

The study aimed to assess the repolarisation indices of ventricular arrhythmia (VA) (mainly Tp-Te interval and Tp-Te/QT ratio) in patients with AA.

METHODS

A group of 98 patients with AA and 75 patients as control were recruited. Many of indices of ventricular arrhythmia were assessed.

RESULTS

Many of indices like QT, QTc, QTpc, Tp-Te/QT, Tp-Te/QTc, Tp-Tec/QTc, S-Tp, S-Tpc, S-Te, S-Tec and fQRS were found to be significantly different in AA group (for all P < 0.05). However, QTp, mean Tp-Te and Tp-Tec were not found different (for all P < 0.05). Aortic diameter (Ao-D) was found to have a positive correlation with QTc, QTpc, S-Tp, S-Tpc, S-Te, S-Tec, fQRS (for all P < 0,05) and negative correlation withTp-Te/QT (P = 0.047). The best cut-off level for prediction of Tp-Te ≥100 ms was found the Ao-D > 43.5 mm in ROC analysis (AUC: 0.69; P = 0.151) with sensitivity 60% and specificity 79.6%.

CONCLUSIONS

Although our study did not find any differences for mean Tp-Te interval between groups, many of other indexes of TDR were found to be significantly different. Ao-D was found to have significant correlations with many indices.

摘要

背景

主动脉瘤(AA)中的心律失常紊乱鲜有报道。

目的

本研究旨在评估主动脉瘤患者室性心律失常(VA)的复极指标(主要为Tp-Te间期和Tp-Te/QT比值)。

方法

招募了98例主动脉瘤患者和75例作为对照的患者。评估了许多室性心律失常指标。

结果

发现AA组中许多指标如QT、QTc、QTpc、Tp-Te/QT、Tp-Te/QTc、Tp-Tec/QTc、S-Tp、S-Tpc、S-Te、S-Tec和fQRS存在显著差异(所有P<0.05)。然而,QTp、平均Tp-Te和Tp-Tec未发现差异(所有P<0.05)。发现主动脉直径(Ao-D)与QTc、QTpc、S-Tp、S-Tpc、S-Te、S-Tec、fQRS呈正相关(所有P<0.05),与Tp-Te/QT呈负相关(P = 0.047)。在ROC分析中,预测Tp-Te≥100 ms的最佳截断水平为Ao-D>43.5 mm(AUC:0.69;P = 0.151),敏感性为60%,特异性为79.6%。

结论

尽管我们的研究未发现两组之间平均Tp-Te间期有任何差异,但发现许多其他TDR指标存在显著差异。发现Ao-D与许多指标有显著相关性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/871b/6454177/09eb2aca4355/OAMJMS-7-943-g001.jpg

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