Boduroglu Yalcin, Son Osman
Department of Cardiology, Ahi Evran University Education and Research Hospital, Kirsehir, Turkey.
Department of Endocrinology, Private Acibadem Hospital, Eskisehir, Turkey.
Open Access Maced J Med Sci. 2019 Mar 13;7(6):943-948. doi: 10.3889/oamjms.2019.191. eCollection 2019 Mar 30.
Arrhythmic disorders in the aortic aneurysm (AA) have been rarely reported.
The study aimed to assess the repolarisation indices of ventricular arrhythmia (VA) (mainly Tp-Te interval and Tp-Te/QT ratio) in patients with AA.
A group of 98 patients with AA and 75 patients as control were recruited. Many of indices of ventricular arrhythmia were assessed.
Many of indices like QT, QTc, QTpc, Tp-Te/QT, Tp-Te/QTc, Tp-Tec/QTc, S-Tp, S-Tpc, S-Te, S-Tec and fQRS were found to be significantly different in AA group (for all P < 0.05). However, QTp, mean Tp-Te and Tp-Tec were not found different (for all P < 0.05). Aortic diameter (Ao-D) was found to have a positive correlation with QTc, QTpc, S-Tp, S-Tpc, S-Te, S-Tec, fQRS (for all P < 0,05) and negative correlation withTp-Te/QT (P = 0.047). The best cut-off level for prediction of Tp-Te ≥100 ms was found the Ao-D > 43.5 mm in ROC analysis (AUC: 0.69; P = 0.151) with sensitivity 60% and specificity 79.6%.
Although our study did not find any differences for mean Tp-Te interval between groups, many of other indexes of TDR were found to be significantly different. Ao-D was found to have significant correlations with many indices.
主动脉瘤（AA）中的心律失常紊乱鲜有报道。
本研究旨在评估主动脉瘤患者室性心律失常（VA）的复极指标（主要为Tp-Te间期和Tp-Te/QT比值）。
招募了98例主动脉瘤患者和75例作为对照的患者。评估了许多室性心律失常指标。
发现AA组中许多指标如QT、QTc、QTpc、Tp-Te/QT、Tp-Te/QTc、Tp-Tec/QTc、S-Tp、S-Tpc、S-Te、S-Tec和fQRS存在显著差异（所有P<0.05）。然而，QTp、平均Tp-Te和Tp-Tec未发现差异（所有P<0.05）。发现主动脉直径（Ao-D）与QTc、QTpc、S-Tp、S-Tpc、S-Te、S-Tec、fQRS呈正相关（所有P<0.05），与Tp-Te/QT呈负相关（P = 0.047）。在ROC分析中，预测Tp-Te≥100 ms的最佳截断水平为Ao-D>43.5 mm（AUC：0.69；P = 0.151），敏感性为60%，特异性为79.6%。
尽管我们的研究未发现两组之间平均Tp-Te间期有任何差异，但发现许多其他TDR指标存在显著差异。发现Ao-D与许多指标有显著相关性。
