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抗合成酶综合征合并心肌炎的误诊病例：当心脏病专家遇到风湿病学。

A misdiagnosed case of antisynthetase syndrome complicated by myocarditis: when the cardiologist deals with rheumatology.

机构信息

Department of Cardiology, San Giovanni di Dio Hospital, Via Fatebenefratelli, 34, 34170, Gorizia, GO, Italy.

Department of Cardiology, San Giovanni di Dio Hospital, Gorizia - San Polo Hospital, Monfalcone, Italy.

出版信息

Clin Rheumatol. 2019 Aug;38(8):2275-2280. doi: 10.1007/s10067-019-04527-z. Epub 2019 Apr 11.

DOI:10.1007/s10067-019-04527-z
PMID:30976930
Abstract

We report a case of a 56-year-old woman with an alleged diagnosis of an acute coronary syndrome that was later correctly identified in our Cardiology Unit as antisynthetase syndrome (AS) with inflammatory cardiac involvement. In this case report, we focus on clinical features of this rare autoimmune disease aiming to provide useful tips to achieve correct differential diagnosis according to updated international guidelines and recommendations, especially in cases of concurrent disease-related myocarditis.

摘要

我们报告了一例 56 岁女性，据称患有急性冠状动脉综合征，后在我院心内科被正确诊断为抗合成酶综合征（AS）合并炎症性心脏受累。在本病例报告中，我们重点介绍了这种罕见自身免疫性疾病的临床特征，旨在根据最新的国际指南和建议提供有用的提示，以实现正确的鉴别诊断，特别是在并发与疾病相关的心肌炎的情况下。

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Autoimmun Rev. 2019 Feb;18(2):113-122. doi: 10.1016/j.autrev.2018.07.013. Epub 2018 Dec 17.
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Fulminant myocarditis: Characteristics, treatment, and outcomes.
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Anatol J Cardiol. 2018 Apr;19(4):279-286. doi: 10.14744/AnatolJCardiol.2017.8170. Epub 2018 Mar 13.
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J Am Coll Cardiol. 2017 Nov 7;70(19):2363-2375. doi: 10.1016/j.jacc.2017.09.023.
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Survival and Left Ventricular Function Changes in Fulminant Versus Nonfulminant Acute Myocarditis.暴发性与非暴发性急性心肌炎的生存和左心室功能变化。
Circulation. 2017 Aug 8;136(6):529-545. doi: 10.1161/CIRCULATIONAHA.117.026386. Epub 2017 Jun 2.
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Myocarditis in Clinical Practice.临床实践中的心肌炎。
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